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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB1 All Species: 30.91
Human Site: S802 Identified Species: 56.67
UniProt: P08183 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08183 NP_000918.2 1280 141479 S802 S M L R Q D V S W F D D P K N
Chimpanzee Pan troglodytes XP_519183 1280 141455 S802 S M L R Q D V S W F D D P K N
Rhesus Macaque Macaca mulatta NP_001028059 1283 141504 S805 S M L R Q D V S W F D D P K N
Dog Lupus familis XP_539461 1269 140189 S794 A M L Y Q D I S W F D D K E N
Cat Felis silvestris
Mouse Mus musculus P21447 1276 140628 S798 S M L R Q D V S W F D D P K N
Rat Rattus norvegicus P43245 1277 141369 S800 S M L R Q D I S W F D D H K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508941 1368 147746 S890 A M L R Q D M S W F D D P R N
Chicken Gallus gallus XP_418636 1307 144961 S829 A I L R Q E I S W F D E P K N
Frog Xenopus laevis NP_001081394 1287 141487 G810 S M L R Q E I G W F D D S K N
Zebra Danio Brachydanio rerio XP_001922717 1340 147081 G864 A I V R Q E I G W F D D N N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00748 1302 143766 G822 A M V N Q E V G W F D D E N N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34712 1321 145045 G843 N V L S Q H I G F F D S P Q N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80725 1286 139009 G809 K V V H M E V G W F D E P E N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96 55.7 N.A. 87.1 80.6 N.A. 62.1 69.6 67.6 56 N.A. 41.1 N.A. 44.5 N.A.
Protein Similarity: 100 99.8 97.7 75.4 N.A. 93.3 90.1 N.A. 76.6 83.6 81.8 73.5 N.A. 60.4 N.A. 62.6 N.A.
P-Site Identity: 100 100 100 66.6 N.A. 100 86.6 N.A. 80 66.6 73.3 46.6 N.A. 53.3 N.A. 40 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 100 93.3 N.A. 100 100 86.6 80 N.A. 73.3 N.A. 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 41.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 62.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 54 0 0 0 0 100 77 0 0 0 % D
% Glu: 0 0 0 0 0 39 0 0 0 0 0 16 8 16 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 100 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 39 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 16 0 0 0 0 47 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 0 0 8 54 0 % K
% Leu: 0 0 77 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 70 0 0 8 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 0 0 0 0 0 0 0 8 16 100 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 62 0 0 % P
% Gln: 0 0 0 0 93 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 70 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 47 0 0 8 0 0 0 62 0 0 0 8 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 16 24 0 0 0 47 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 93 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _