KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB1
All Species:
7.58
Human Site:
S90
Identified Species:
13.89
UniProt:
P08183
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08183
NP_000918.2
1280
141479
S90
G
N
L
E
D
L
M
S
N
I
T
N
R
S
D
Chimpanzee
Pan troglodytes
XP_519183
1280
141455
S90
G
N
L
E
D
L
M
S
N
I
T
N
R
S
D
Rhesus Macaque
Macaca mulatta
NP_001028059
1283
141504
F93
G
D
L
G
A
L
L
F
N
N
T
N
S
S
N
Dog
Lupus familis
XP_539461
1269
140189
V82
N
L
I
S
G
C
L
V
K
T
N
T
T
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
P21447
1276
140628
K86
A
S
V
G
N
V
S
K
N
S
T
N
M
S
E
Rat
Rattus norvegicus
P43245
1277
141369
I89
D
P
H
S
D
R
A
I
T
N
Q
S
E
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508941
1368
147746
I184
S
F
I
P
T
G
N
I
S
A
A
G
N
F
S
Chicken
Gallus gallus
XP_418636
1307
144961
T121
N
F
S
L
L
N
S
T
S
V
N
F
S
M
E
Frog
Xenopus laevis
NP_001081394
1287
141487
V100
S
F
V
N
V
G
Q
V
D
T
G
N
F
T
W
Zebra Danio
Brachydanio rerio
XP_001922717
1340
147081
F134
N
F
T
S
N
F
T
F
T
L
N
N
T
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00748
1302
143766
G96
V
H
A
L
P
L
F
G
G
G
K
T
L
T
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34712
1321
145045
N114
N
E
Q
I
V
I
N
N
N
G
S
T
F
L
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80725
1286
139009
S103
T
N
T
T
D
K
V
S
K
V
A
L
K
F
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96
55.7
N.A.
87.1
80.6
N.A.
62.1
69.6
67.6
56
N.A.
41.1
N.A.
44.5
N.A.
Protein Similarity:
100
99.8
97.7
75.4
N.A.
93.3
90.1
N.A.
76.6
83.6
81.8
73.5
N.A.
60.4
N.A.
62.6
N.A.
P-Site Identity:
100
100
46.6
0
N.A.
26.6
6.6
N.A.
0
0
6.6
13.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
66.6
20
N.A.
60
20
N.A.
13.3
26.6
26.6
26.6
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
8
0
0
8
16
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
31
0
0
0
8
0
0
0
0
0
16
% D
% Glu:
0
8
0
16
0
0
0
0
0
0
0
0
8
0
16
% E
% Phe:
0
31
0
0
0
8
8
16
0
0
0
8
16
16
0
% F
% Gly:
24
0
0
16
8
16
0
8
8
16
8
8
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
8
0
8
0
16
0
16
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
8
0
8
16
0
8
0
8
0
0
% K
% Leu:
0
8
24
16
8
31
16
0
0
8
0
8
8
8
0
% L
% Met:
0
0
0
0
0
0
16
0
0
0
0
0
8
8
0
% M
% Asn:
31
24
0
8
16
8
16
8
39
16
24
47
8
8
24
% N
% Pro:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
16
0
0
% R
% Ser:
16
8
8
24
0
0
16
24
16
8
8
8
16
39
8
% S
% Thr:
8
0
16
8
8
0
8
8
16
16
31
24
16
16
8
% T
% Val:
8
0
16
0
16
8
8
16
0
16
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _