Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR3C2 All Species: 16.06
Human Site: S408 Identified Species: 39.26
UniProt: P08235 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08235 NP_000892.2 984 107067 S408 E P D G A F S S S C L G G N S
Chimpanzee Pan troglodytes A7X8B3 933 98902 V406 R S P R S Y L V A G A N P A A
Rhesus Macaque Macaca mulatta XP_001099653 984 107008 S408 E P D G A F S S S C L G G N S
Dog Lupus familis XP_532685 973 105873 S405 E P D G A F S S S C L G G N N
Cat Felis silvestris
Mouse Mus musculus Q8VII8 978 106429 S408 E P D G A F S S S C L G G N N
Rat Rattus norvegicus P22199 981 106719 S408 S E P D G A F S S S C L G G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513606 990 107642 F408 K P E P D G A F S S S C L G G
Chicken Gallus gallus P07812 786 85725 L267 P S V P A A D L A E Y G Y P P
Frog Xenopus laevis Q91573 612 67928 S93 G I L G P P V S S F G D G F E
Zebra Danio Brachydanio rerio NP_001093873 970 105577 M407 L G S S K S A M S N S P F V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.7 95.5 93.5 N.A. 90.6 90.1 N.A. 87.8 33.9 47.5 51.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 44.8 97.1 95.5 N.A. 95 94.1 N.A. 93.2 47.8 54.4 66.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 93.3 N.A. 93.3 20 N.A. 13.3 13.3 26.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 26.6 N.A. 33.3 20 26.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 50 20 20 0 20 0 10 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 40 10 10 0 0 0 % C
% Asp: 0 0 40 10 10 0 10 0 0 0 0 10 0 0 0 % D
% Glu: 40 10 10 0 0 0 0 0 0 10 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 40 10 10 0 10 0 0 10 10 0 % F
% Gly: 10 10 0 50 10 10 0 0 0 10 10 50 60 20 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 0 10 10 0 0 40 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 10 0 40 30 % N
% Pro: 10 50 20 20 10 10 0 0 0 0 0 10 10 10 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 20 10 10 10 10 40 60 80 20 20 0 0 0 20 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 10 0 0 0 10 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _