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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR3C2
All Species:
13.33
Human Site:
S440
Identified Species:
32.59
UniProt:
P08235
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08235
NP_000892.2
984
107067
S440
K
H
S
C
S
G
T
S
F
K
G
N
P
T
V
Chimpanzee
Pan troglodytes
A7X8B3
933
98902
A438
P
S
R
P
G
E
A
A
V
T
A
A
P
A
S
Rhesus Macaque
Macaca mulatta
XP_001099653
984
107008
S440
K
H
S
C
S
G
T
S
F
K
G
N
P
T
V
Dog
Lupus familis
XP_532685
973
105873
S437
K
H
S
C
S
G
T
S
F
K
G
N
P
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VII8
978
106429
S440
K
H
S
C
S
G
A
S
F
K
G
N
P
T
V
Rat
Rattus norvegicus
P22199
981
106719
A440
S
K
H
S
C
S
G
A
S
F
K
G
N
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513606
990
107642
G440
S
T
K
H
S
C
S
G
T
P
F
K
G
N
Q
Chicken
Gallus gallus
P07812
786
85725
G299
K
I
K
E
E
G
V
G
L
P
A
A
P
P
P
Frog
Xenopus laevis
Q91573
612
67928
E125
E
D
S
S
F
Y
P
E
N
N
M
P
S
S
A
Zebra Danio
Brachydanio rerio
NP_001093873
970
105577
G439
A
E
P
Q
H
S
L
G
C
F
P
S
T
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
95.5
93.5
N.A.
90.6
90.1
N.A.
87.8
33.9
47.5
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
44.8
97.1
95.5
N.A.
95
94.1
N.A.
93.2
47.8
54.4
66.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
93.3
0
N.A.
6.6
20
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
6.6
N.A.
13.3
20
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
20
20
0
0
20
20
0
10
10
% A
% Cys:
0
0
0
40
10
10
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
0
10
10
10
0
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
10
0
0
0
40
20
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
50
10
30
0
0
40
10
10
0
0
% G
% His:
0
40
10
10
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
50
10
20
0
0
0
0
0
0
40
10
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
10
0
40
10
10
0
% N
% Pro:
10
0
10
10
0
0
10
0
0
20
10
10
60
20
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
10
50
20
50
20
10
40
10
0
0
10
10
10
10
% S
% Thr:
0
10
0
0
0
0
30
0
10
10
0
0
10
40
20
% T
% Val:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _