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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GUSB All Species: 11.21
Human Site: S638 Identified Species: 27.41
UniProt: P08236 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08236 NP_000172.1 651 74732 S638 N E T R Y P H S V A K S Q C L
Chimpanzee Pan troglodytes XP_001138789 651 74713 S638 N E T R Y P H S V A K S Q C L
Rhesus Macaque Macaca mulatta XP_001087699 428 50104 I416 E T R Y P Y S I A K S Q C L E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P12265 648 74221 S634 N E T G G H G S G P R T Q C F
Rat Rattus norvegicus P06760 648 74775 S634 N E T R G Y G S V P R T Q C M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034405 657 74550 L632 P K S A A F V L R E R Y W K I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700122 511 57690 S499 Y W R I A N E S G V L P T W S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611395 656 75148 S642 G R D L D Q C S F P E D L F T
Honey Bee Apis mellifera XP_393305 669 76899 E648 Q K E L D G T E I P T D F E D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781168 630 71499 L617 P K M E A H V L K E R Y L E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 60.5 N.A. N.A. 74.6 75.1 N.A. N.A. 68.6 N.A. 52.3 N.A. 45.7 43.3 N.A. 55.6
Protein Similarity: 100 99.8 62.9 N.A. N.A. 85.4 86.3 N.A. N.A. 80.2 N.A. 64.9 N.A. 63.8 61.1 N.A. 69.5
P-Site Identity: 100 100 0 N.A. N.A. 40 53.3 N.A. N.A. 0 N.A. 6.6 N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 100 0 N.A. N.A. 53.3 73.3 N.A. N.A. 26.6 N.A. 6.6 N.A. 13.3 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 30 0 0 0 10 20 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 10 40 0 % C
% Asp: 0 0 10 0 20 0 0 0 0 0 0 20 0 0 10 % D
% Glu: 10 40 10 10 0 0 10 10 0 20 10 0 0 20 10 % E
% Phe: 0 0 0 0 0 10 0 0 10 0 0 0 10 10 10 % F
% Gly: 10 0 0 10 20 10 20 0 20 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 20 20 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 10 10 0 0 0 0 0 10 % I
% Lys: 0 30 0 0 0 0 0 0 10 10 20 0 0 10 0 % K
% Leu: 0 0 0 20 0 0 0 20 0 0 10 0 20 10 30 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 40 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 20 0 0 0 10 20 0 0 0 40 0 10 0 0 0 % P
% Gln: 10 0 0 0 0 10 0 0 0 0 0 10 40 0 0 % Q
% Arg: 0 10 20 30 0 0 0 0 10 0 40 0 0 0 0 % R
% Ser: 0 0 10 0 0 0 10 60 0 0 10 20 0 0 10 % S
% Thr: 0 10 40 0 0 0 10 0 0 0 10 20 10 0 10 % T
% Val: 0 0 0 0 0 0 20 0 30 10 0 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 10 10 0 % W
% Tyr: 10 0 0 10 20 20 0 0 0 0 0 20 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _