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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GUSB
All Species:
6.97
Human Site:
T274
Identified Species:
17.04
UniProt:
P08236
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08236
NP_000172.1
651
74732
T274
N
K
V
V
A
N
G
T
G
T
Q
G
Q
L
K
Chimpanzee
Pan troglodytes
XP_001138789
651
74713
T274
N
K
V
V
A
N
G
T
G
T
Q
G
Q
L
K
Rhesus Macaque
Macaca mulatta
XP_001087699
428
50104
D94
S
Q
D
W
R
L
W
D
F
V
G
W
V
W
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P12265
648
74221
A270
D
E
D
G
K
V
V
A
H
G
T
G
N
Q
G
Rat
Rattus norvegicus
P06760
648
74775
A270
D
E
D
G
K
I
V
A
R
G
T
G
N
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034405
657
74550
D284
G
K
V
V
A
T
G
D
G
P
S
G
E
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700122
511
57690
S177
Y
S
M
E
V
Q
A
S
A
E
D
G
Q
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611395
656
75148
S281
I
L
V
A
N
A
T
S
D
Q
K
L
G
G
K
Honey Bee
Apis mellifera
XP_393305
669
76899
P287
D
N
L
A
V
Q
E
P
I
Y
G
F
S
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781168
630
71499
V268
L
D
R
A
G
L
V
V
A
S
S
T
K
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
60.5
N.A.
N.A.
74.6
75.1
N.A.
N.A.
68.6
N.A.
52.3
N.A.
45.7
43.3
N.A.
55.6
Protein Similarity:
100
99.8
62.9
N.A.
N.A.
85.4
86.3
N.A.
N.A.
80.2
N.A.
64.9
N.A.
63.8
61.1
N.A.
69.5
P-Site Identity:
100
100
0
N.A.
N.A.
6.6
6.6
N.A.
N.A.
60
N.A.
13.3
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
13.3
N.A.
N.A.
20
20
N.A.
N.A.
66.6
N.A.
26.6
N.A.
26.6
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
30
30
10
10
20
20
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
10
30
0
0
0
0
20
10
0
10
0
0
0
10
% D
% Glu:
0
20
0
10
0
0
10
0
0
10
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% F
% Gly:
10
0
0
20
10
0
30
0
30
20
20
60
10
20
20
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
30
0
0
20
0
0
0
0
0
10
0
10
0
40
% K
% Leu:
10
10
10
0
0
20
0
0
0
0
0
10
0
30
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
20
10
0
0
10
20
0
0
0
0
0
0
20
0
10
% N
% Pro:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
20
0
0
0
10
20
0
30
10
0
% Q
% Arg:
0
0
10
0
10
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
0
0
0
20
0
10
20
0
10
0
0
% S
% Thr:
0
0
0
0
0
10
10
20
0
20
20
10
0
10
10
% T
% Val:
0
0
40
30
20
10
30
10
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
10
0
0
10
0
0
0
0
10
0
10
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _