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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFKM
All Species:
0
Human Site:
S137
Identified Species:
0
UniProt:
P08237
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08237
NP_000280.1
780
85183
S137
S
E
W
S
D
L
L
S
D
L
Q
K
A
G
K
Chimpanzee
Pan troglodytes
XP_001150233
780
84936
E137
S
E
W
G
S
L
L
E
E
L
V
A
E
G
K
Rhesus Macaque
Macaca mulatta
XP_001096244
851
93251
G208
S
E
W
S
D
L
L
G
D
L
Q
K
A
G
K
Dog
Lupus familis
XP_544922
751
82459
N138
G
L
V
G
S
I
D
N
D
F
C
G
T
D
M
Cat
Felis silvestris
Mouse
Mus musculus
P47857
780
85250
N137
S
E
W
S
D
L
L
N
D
L
Q
K
D
G
K
Rat
Rattus norvegicus
P47858
780
85541
N137
S
E
W
S
D
L
L
N
D
L
Q
K
D
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511162
864
94802
E217
E
E
W
S
G
L
L
E
E
L
A
R
E
G
K
Chicken
Gallus gallus
NP_989554
769
83907
L129
S
S
L
L
A
E
L
L
K
T
G
G
I
T
A
Frog
Xenopus laevis
NP_001086921
808
88294
A166
S
E
W
S
G
L
L
A
D
L
V
K
A
D
T
Zebra Danio
Brachydanio rerio
NP_001004575
784
85614
K139
T
E
W
S
D
L
L
K
D
H
V
S
K
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52034
788
86630
D139
Q
E
W
S
S
L
L
D
E
L
V
K
N
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27483
756
83282
E130
E
E
W
G
R
F
G
E
E
L
F
A
E
G
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P16862
959
104599
E319
S
E
W
P
S
L
I
E
E
L
L
K
T
N
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.5
90.4
67.6
N.A.
97.8
96.6
N.A.
65.2
81.2
81.4
77.8
N.A.
58.7
N.A.
39.6
N.A.
Protein Similarity:
100
82.8
91.1
81.7
N.A.
99
98.2
N.A.
76.2
90.1
90.3
88.7
N.A.
75.7
N.A.
57.6
N.A.
P-Site Identity:
100
53.3
93.3
6.6
N.A.
86.6
86.6
N.A.
53.3
13.3
66.6
60
N.A.
46.6
N.A.
33.3
N.A.
P-Site Similarity:
100
60
93.3
20
N.A.
93.3
93.3
N.A.
66.6
13.3
73.3
66.6
N.A.
53.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
0
8
16
24
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
39
0
8
8
54
0
0
0
16
16
0
% D
% Glu:
16
85
0
0
0
8
0
31
39
0
0
0
24
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% F
% Gly:
8
0
0
24
16
0
8
8
0
0
8
16
0
62
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
0
0
54
8
8
62
% K
% Leu:
0
8
8
8
0
77
77
8
0
77
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
24
0
0
0
0
8
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% R
% Ser:
62
8
0
62
31
0
0
8
0
0
0
8
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
0
16
8
16
% T
% Val:
0
0
8
0
0
0
0
0
0
0
31
0
0
0
0
% V
% Trp:
0
0
85
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _