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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPR All Species: 24.85
Human Site: S151 Identified Species: 42.05
UniProt: P08240 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08240 NP_003130.2 638 69811 S151 K A K K P V R S M I E T R G E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112588 638 69763 S151 K A K K P V R S M I E T R G E
Dog Lupus familis XP_546411 612 66844 G145 A K N S K K K G A K K E S S D
Cat Felis silvestris
Mouse Mus musculus Q9DBG7 636 69604 S151 K A K K P V R S M I E T R G E
Rat Rattus norvegicus NP_001029322 636 69638 S151 K A K K P V R S M I E T R G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034366 644 71178 C154 K S Q K T V K C M I E T R G E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697518 650 71144 S153 K S K K T V K S M I E T K D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U5L1 614 67777 S146 K S K K T V A S M I Q D D K K
Honey Bee Apis mellifera XP_395013 605 68213 S149 K S K K T V A S M I E R K D D
Nematode Worm Caenorhab. elegans NP_741303 625 69292 I154 S A K S Q K T I D S L I V S R
Sea Urchin Strong. purpuratus XP_001188635 584 65767 E154 M I I D P S K E E K N I T N K
Poplar Tree Populus trichocarpa XP_002309350 624 68615 N167 S E A N E G G N G D D G K G R
Maize Zea mays NP_001130574 625 68471 S170 G S G A K D D S D G D G Y G N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32916 621 69260 D146 D I L Q G I E D D L K K F E Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 92.9 N.A. 97.1 97.6 N.A. N.A. 78.7 N.A. 67.3 N.A. 51.4 58.1 49 52.8
Protein Similarity: 100 N.A. 99.6 93.7 N.A. 98.2 98.7 N.A. N.A. 87.4 N.A. 78.7 N.A. 69.7 71.6 66.1 63.9
P-Site Identity: 100 N.A. 100 0 N.A. 100 100 N.A. N.A. 66.6 N.A. 60 N.A. 46.6 53.3 13.3 6.6
P-Site Similarity: 100 N.A. 100 20 N.A. 100 100 N.A. N.A. 86.6 N.A. 80 N.A. 66.6 73.3 13.3 20
Percent
Protein Identity: 43.2 43.7 N.A. N.A. 31.6 N.A.
Protein Similarity: 59.5 61.1 N.A. N.A. 51.7 N.A.
P-Site Identity: 6.6 13.3 N.A. N.A. 0 N.A.
P-Site Similarity: 26.6 26.6 N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 36 8 8 0 0 15 0 8 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 0 8 8 8 22 8 15 8 8 15 15 % D
% Glu: 0 8 0 0 8 0 8 8 8 0 50 8 0 8 36 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 0 8 0 8 8 8 8 8 8 0 15 0 50 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 8 0 0 8 0 8 0 58 0 15 0 0 0 % I
% Lys: 58 8 58 58 15 15 29 0 0 15 15 8 22 8 15 % K
% Leu: 0 0 8 0 0 0 0 0 0 8 8 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 58 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 8 0 0 8 0 0 8 8 % N
% Pro: 0 0 0 0 36 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 8 8 0 0 0 0 0 8 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 29 0 0 0 0 8 36 0 15 % R
% Ser: 15 36 0 15 0 8 0 58 0 8 0 0 8 15 0 % S
% Thr: 0 0 0 0 29 0 8 0 0 0 0 43 8 0 0 % T
% Val: 0 0 0 0 0 58 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _