Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPR All Species: 21.21
Human Site: S332 Identified Species: 35.9
UniProt: P08240 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08240 NP_003130.2 638 69811 S332 K G L V G S K S L S R E D M E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112588 638 69763 S332 K G L V G S K S L S R E D M E
Dog Lupus familis XP_546411 612 66844 S306 K G L V G S K S L S R E D M E
Cat Felis silvestris
Mouse Mus musculus Q9DBG7 636 69604 L331 G L V G S K S L S R E D M E S
Rat Rattus norvegicus NP_001029322 636 69638 L331 G L V G S K S L S R E D M E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034366 644 71178 S338 K G L V G S K S L T R Q N M D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697518 650 71144 N344 K G L V G S K N L T Q E D M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U5L1 614 67777 T309 K G I V G A K T M S L A D L Q
Honey Bee Apis mellifera XP_395013 605 68213 L310 H E D M A P V L D K L K D H L
Nematode Worm Caenorhab. elegans NP_741303 625 69292 K326 K G L V G E K K L S A E D L N
Sea Urchin Strong. purpuratus XP_001188635 584 65767 T320 R G L V G S K T L D K E T M A
Poplar Tree Populus trichocarpa XP_002309350 624 68615 N332 Q S I A G K A N L E K A D L E
Maize Zea mays NP_001130574 625 68471 L343 K S D L Q P A L K A L K D R L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32916 621 69260 L315 E S D L K S V L E K L T Q Q L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 92.9 N.A. 97.1 97.6 N.A. N.A. 78.7 N.A. 67.3 N.A. 51.4 58.1 49 52.8
Protein Similarity: 100 N.A. 99.6 93.7 N.A. 98.2 98.7 N.A. N.A. 87.4 N.A. 78.7 N.A. 69.7 71.6 66.1 63.9
P-Site Identity: 100 N.A. 100 100 N.A. 0 0 N.A. N.A. 73.3 N.A. 80 N.A. 46.6 6.6 66.6 60
P-Site Similarity: 100 N.A. 100 100 N.A. 13.3 13.3 N.A. N.A. 100 N.A. 100 N.A. 86.6 20 73.3 80
Percent
Protein Identity: 43.2 43.7 N.A. N.A. 31.6 N.A.
Protein Similarity: 59.5 61.1 N.A. N.A. 51.7 N.A.
P-Site Identity: 26.6 13.3 N.A. N.A. 6.6 N.A.
P-Site Similarity: 60 33.3 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 8 15 0 0 8 8 15 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 22 0 0 0 0 0 8 8 0 15 65 0 8 % D
% Glu: 8 8 0 0 0 8 0 0 8 8 15 43 0 15 36 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 58 0 15 65 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 58 0 0 0 8 22 58 8 8 15 15 15 0 0 0 % K
% Leu: 0 15 50 15 0 0 0 36 58 0 29 0 0 22 22 % L
% Met: 0 0 0 8 0 0 0 0 8 0 0 0 15 43 0 % M
% Asn: 0 0 0 0 0 0 0 15 0 0 0 0 8 0 8 % N
% Pro: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 8 0 0 0 0 0 8 8 8 8 8 % Q
% Arg: 8 0 0 0 0 0 0 0 0 15 29 0 0 8 0 % R
% Ser: 0 22 0 0 15 50 15 29 15 36 0 0 0 0 15 % S
% Thr: 0 0 0 0 0 0 0 15 0 15 0 8 8 0 0 % T
% Val: 0 0 15 58 0 0 15 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _