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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPR All Species: 19.7
Human Site: T155 Identified Species: 33.33
UniProt: P08240 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08240 NP_003130.2 638 69811 T155 P V R S M I E T R G E K P K E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112588 638 69763 T155 P V R S M I E T R G E K P K E
Dog Lupus familis XP_546411 612 66844 E149 K K K G A K K E S S D G P L A
Cat Felis silvestris
Mouse Mus musculus Q9DBG7 636 69604 T155 P V R S M I E T R G E K T K E
Rat Rattus norvegicus NP_001029322 636 69638 T155 P V R S M I E T R G E K T K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034366 644 71178 T158 T V K C M I E T R G E K P K E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697518 650 71144 T157 T V K S M I E T K D A D K S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U5L1 614 67777 D150 T V A S M I Q D D K K P V E K
Honey Bee Apis mellifera XP_395013 605 68213 R153 T V A S M I E R K D D K E N K
Nematode Worm Caenorhab. elegans NP_741303 625 69292 I158 Q K T I D S L I V S R P G Q K
Sea Urchin Strong. purpuratus XP_001188635 584 65767 I158 P S K E E K N I T N K A A K K
Poplar Tree Populus trichocarpa XP_002309350 624 68615 G171 E G G N G D D G K G R K L E N
Maize Zea mays NP_001130574 625 68471 G174 K D D S D G D G Y G N Q D H R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32916 621 69260 K150 G I E D D L K K F E Q Y F R I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 92.9 N.A. 97.1 97.6 N.A. N.A. 78.7 N.A. 67.3 N.A. 51.4 58.1 49 52.8
Protein Similarity: 100 N.A. 99.6 93.7 N.A. 98.2 98.7 N.A. N.A. 87.4 N.A. 78.7 N.A. 69.7 71.6 66.1 63.9
P-Site Identity: 100 N.A. 100 6.6 N.A. 93.3 93.3 N.A. N.A. 80 N.A. 40 N.A. 26.6 40 0 13.3
P-Site Similarity: 100 N.A. 100 26.6 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 60 N.A. 53.3 60 13.3 33.3
Percent
Protein Identity: 43.2 43.7 N.A. N.A. 31.6 N.A.
Protein Similarity: 59.5 61.1 N.A. N.A. 51.7 N.A.
P-Site Identity: 13.3 13.3 N.A. N.A. 0 N.A.
P-Site Similarity: 40 26.6 N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 0 8 0 0 0 0 0 8 8 8 0 8 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 8 22 8 15 8 8 15 15 8 8 0 0 % D
% Glu: 8 0 8 8 8 0 50 8 0 8 36 0 8 15 36 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % F
% Gly: 8 8 8 8 8 8 0 15 0 50 0 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 0 8 0 58 0 15 0 0 0 0 0 0 8 % I
% Lys: 15 15 29 0 0 15 15 8 22 8 15 50 8 43 36 % K
% Leu: 0 0 0 0 0 8 8 0 0 0 0 0 8 8 0 % L
% Met: 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 0 0 8 8 0 0 8 8 % N
% Pro: 36 0 0 0 0 0 0 0 0 0 0 15 29 0 0 % P
% Gln: 8 0 0 0 0 0 8 0 0 0 8 8 0 8 0 % Q
% Arg: 0 0 29 0 0 0 0 8 36 0 15 0 0 8 8 % R
% Ser: 0 8 0 58 0 8 0 0 8 15 0 0 0 8 0 % S
% Thr: 29 0 8 0 0 0 0 43 8 0 0 0 15 0 0 % T
% Val: 0 58 0 0 0 0 0 0 8 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _