KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSG
All Species:
11.82
Human Site:
S42
Identified Species:
37.14
UniProt:
P08311
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08311
NP_001902.1
255
28837
S42
M
A
Y
L
Q
I
Q
S
P
A
G
Q
S
R
C
Chimpanzee
Pan troglodytes
XP_522810
255
28862
S42
M
A
Y
L
Q
I
Q
S
P
A
G
Q
S
R
C
Rhesus Macaque
Macaca mulatta
XP_001114339
255
29054
S42
M
A
Y
L
Q
I
Q
S
P
R
G
R
S
S
C
Dog
Lupus familis
XP_850688
312
34175
P43
A
Y
L
Q
I
R
S
P
N
G
G
S
S
A
C
Cat
Felis silvestris
Mouse
Mus musculus
P28293
261
29077
S42
M
A
F
L
L
I
Q
S
P
E
G
L
S
A
C
Rat
Rattus norvegicus
P18291
248
27307
E43
A
Y
L
Q
I
M
D
E
Y
S
G
S
K
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90627
248
26051
L43
A
A
P
Y
Q
V
S
L
N
S
G
Y
H
F
C
Frog
Xenopus laevis
P19799
243
25473
L38
S
V
P
Y
I
V
S
L
N
S
G
Y
H
F
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
85.4
53.5
N.A.
65.9
54.1
N.A.
N.A.
33.3
34.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
92.1
63.7
N.A.
78.1
70.1
N.A.
N.A.
52.1
51.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
20
N.A.
66.6
13.3
N.A.
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
20
N.A.
73.3
33.3
N.A.
N.A.
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
63
0
0
0
0
0
0
0
25
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% C
% Asp:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
13
0
13
0
0
0
0
0
% E
% Phe:
0
0
13
0
0
0
0
0
0
0
0
0
0
25
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
13
100
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% H
% Ile:
0
0
0
0
38
50
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
13
13
0
% K
% Leu:
0
0
25
50
13
0
0
25
0
0
0
13
0
0
0
% L
% Met:
50
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
38
0
0
0
0
0
0
% N
% Pro:
0
0
25
0
0
0
0
13
50
0
0
0
0
0
0
% P
% Gln:
0
0
0
25
50
0
50
0
0
0
0
25
0
0
0
% Q
% Arg:
0
0
0
0
0
13
0
0
0
13
0
13
0
25
0
% R
% Ser:
13
0
0
0
0
0
38
50
0
38
0
25
63
13
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
13
0
0
0
25
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
25
38
25
0
0
0
0
13
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _