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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADH4
All Species:
1.21
Human Site:
S124
Identified Species:
2.96
UniProt:
P08319
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08319
NP_000661.2
380
40222
S124
S
N
L
K
S
P
A
S
D
Q
Q
L
M
E
D
Chimpanzee
Pan troglodytes
Q5R1W2
375
39808
T123
D
L
G
N
P
R
G
T
L
Q
D
G
T
R
R
Rhesus Macaque
Macaca mulatta
P28469
375
39894
T123
D
V
S
N
P
R
G
T
L
Q
D
G
T
S
R
Dog
Lupus familis
XP_535665
379
40964
V124
S
L
V
K
N
P
I
V
D
Q
E
L
M
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYY9
377
40163
I123
R
N
F
K
Y
P
T
I
D
Q
E
L
M
E
D
Rat
Rattus norvegicus
Q64563
377
40258
I123
R
N
F
K
Y
P
T
I
D
Q
E
L
M
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23991
376
39789
G123
D
L
S
S
S
P
T
G
L
M
A
D
G
T
T
Frog
Xenopus laevis
NP_001086427
376
39998
F124
R
I
T
Q
G
K
G
F
M
P
D
G
T
S
R
Zebra Danio
Brachydanio rerio
NP_571924
376
40014
Q120
C
Q
K
I
R
V
T
Q
G
Q
G
L
M
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46415
379
40371
V125
R
L
T
Q
G
A
G
V
M
P
E
G
T
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.2
59.4
80.5
N.A.
72.1
72.1
N.A.
N.A.
58.9
63.6
65
N.A.
57.1
N.A.
N.A.
N.A.
Protein Similarity:
100
75.2
74.2
87.6
N.A.
85.2
84.4
N.A.
N.A.
73.4
78.9
77.8
N.A.
73.6
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
60
N.A.
60
60
N.A.
N.A.
13.3
0
26.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
80
N.A.
66.6
66.6
N.A.
N.A.
13.3
6.6
26.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
0
0
0
0
0
0
0
40
0
30
10
0
0
50
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
40
0
0
40
0
% E
% Phe:
0
0
20
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
20
0
40
10
10
0
10
40
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
0
0
10
20
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
40
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
40
10
0
0
0
0
0
30
0
0
50
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
20
10
0
0
50
0
0
% M
% Asn:
0
30
0
20
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
50
0
0
0
20
0
0
0
10
0
% P
% Gln:
0
10
0
20
0
0
0
10
0
70
10
0
0
0
0
% Q
% Arg:
40
0
0
0
10
20
0
0
0
0
0
0
0
10
40
% R
% Ser:
20
0
20
10
20
0
0
10
0
0
0
0
0
30
0
% S
% Thr:
0
0
20
0
0
0
40
20
0
0
0
0
40
10
10
% T
% Val:
0
10
10
0
0
10
0
20
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _