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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MME All Species: 13.94
Human Site: T15 Identified Species: 27.88
UniProt: P08473 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08473 NP_000893.2 750 85514 T15 M D I T D I N T P K P K K K Q
Chimpanzee Pan troglodytes XP_516827 750 85495 T15 M D I T D I N T P K P K K K Q
Rhesus Macaque Macaca mulatta XP_001105708 750 85452 T15 M D I T D I N T P K P K K K Q
Dog Lupus familis XP_534313 749 85531 T15 M D I T D I S T P R P K K Q R
Cat Felis silvestris
Mouse Mus musculus Q61391 750 85683 A15 M D I T D I N A P K P K K K Q
Rat Rattus norvegicus P07861 750 85777 A15 M D I T D I N A P K P K K K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001004412 750 85321 A15 M D I T E M N A P K P K K K L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689191 755 86752 T23 K P R K H R W T V V E I G L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_511056 849 96515 A131 G A A I G A L A I Y F A S V H
Honey Bee Apis mellifera XP_392502 776 89056 L60 P G N R R K S L G I T R A T S
Nematode Worm Caenorhab. elegans O16796 848 97043 D119 T E H A G F G D P T E N P T K
Sea Urchin Strong. purpuratus XP_781407 763 86739 L41 L V V I V V V L A L L T V S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.9 93 N.A. 94.1 94.2 N.A. N.A. 78.8 N.A. 56.2 N.A. 36.2 39.9 32.9 38.6
Protein Similarity: 100 99.7 99.5 97 N.A. 97.7 97.8 N.A. N.A. 88.8 N.A. 74.5 N.A. 53.9 59.2 52.1 59.9
P-Site Identity: 100 100 100 73.3 N.A. 93.3 93.3 N.A. N.A. 73.3 N.A. 6.6 N.A. 0 0 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 6.6 N.A. 0 13.3 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 9 0 9 0 34 9 0 0 9 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 59 0 0 50 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 0 9 0 0 0 0 0 17 0 0 0 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % F
% Gly: 9 9 0 0 17 0 9 0 9 0 0 0 9 0 0 % G
% His: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 59 17 0 50 0 0 9 9 0 9 0 0 0 % I
% Lys: 9 0 0 9 0 9 0 0 0 50 0 59 59 50 9 % K
% Leu: 9 0 0 0 0 0 9 17 0 9 9 0 0 9 17 % L
% Met: 59 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 50 0 0 0 0 9 0 0 0 % N
% Pro: 9 9 0 0 0 0 0 0 67 0 59 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 42 % Q
% Arg: 0 0 9 9 9 9 0 0 0 9 0 9 0 0 9 % R
% Ser: 0 0 0 0 0 0 17 0 0 0 0 0 9 9 17 % S
% Thr: 9 0 0 59 0 0 0 42 0 9 9 9 0 17 0 % T
% Val: 0 9 9 0 9 9 9 0 9 9 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _