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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MME
All Species:
23.64
Human Site:
T25
Identified Species:
47.27
UniProt:
P08473
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08473
NP_000893.2
750
85514
T25
P
K
K
K
Q
R
W
T
P
L
E
I
S
L
S
Chimpanzee
Pan troglodytes
XP_516827
750
85495
T25
P
K
K
K
Q
R
W
T
P
L
E
I
S
L
S
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
T25
P
K
K
K
Q
R
W
T
P
L
E
I
S
L
S
Dog
Lupus familis
XP_534313
749
85531
S25
P
K
K
Q
R
W
T
S
L
E
I
S
L
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61391
750
85683
T25
P
K
K
K
Q
R
W
T
P
L
E
I
S
L
S
Rat
Rattus norvegicus
P07861
750
85777
T25
P
K
K
K
Q
R
W
T
P
L
E
I
S
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001004412
750
85321
S25
P
K
K
K
L
R
W
S
G
L
E
I
G
L
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
V33
E
I
G
L
S
V
I
V
L
L
M
S
C
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
C141
F
A
S
V
H
Q
R
C
H
L
Y
R
L
E
P
Honey Bee
Apis mellifera
XP_392502
776
89056
R70
T
R
A
T
S
I
R
R
R
G
P
A
N
R
Q
Nematode Worm
Caenorhab. elegans
O16796
848
97043
E129
E
N
P
T
K
T
A
E
D
P
R
V
P
P
I
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
A51
L
T
V
S
L
I
V
A
T
V
V
I
A
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.9
93
N.A.
94.1
94.2
N.A.
N.A.
78.8
N.A.
56.2
N.A.
36.2
39.9
32.9
38.6
Protein Similarity:
100
99.7
99.5
97
N.A.
97.7
97.8
N.A.
N.A.
88.8
N.A.
74.5
N.A.
53.9
59.2
52.1
59.9
P-Site Identity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
66.6
N.A.
6.6
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
N.A.
80
N.A.
6.6
N.A.
13.3
13.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
9
9
0
0
0
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% D
% Glu:
17
0
0
0
0
0
0
9
0
9
50
0
0
9
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
9
9
0
0
9
0
0
% G
% His:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
17
9
0
0
0
9
59
0
0
9
% I
% Lys:
0
59
59
50
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
9
17
0
0
0
17
67
0
0
17
50
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
59
0
9
0
0
0
0
0
42
9
9
0
9
9
9
% P
% Gln:
0
0
0
9
42
9
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
0
0
9
50
17
9
9
0
9
9
0
9
0
% R
% Ser:
0
0
9
9
17
0
0
17
0
0
0
17
42
17
42
% S
% Thr:
9
9
0
17
0
9
9
42
9
0
0
0
0
0
9
% T
% Val:
0
0
9
9
0
9
9
9
0
9
9
9
0
0
9
% V
% Trp:
0
0
0
0
0
9
50
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _