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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MME
All Species:
29.39
Human Site:
Y482
Identified Species:
58.79
UniProt:
P08473
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08473
NP_000893.2
750
85514
Y482
A
I
K
E
R
I
G
Y
P
D
D
I
V
S
N
Chimpanzee
Pan troglodytes
XP_516827
750
85495
Y482
A
I
K
E
R
I
G
Y
P
D
D
I
V
S
N
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
Y482
A
I
K
E
R
I
G
Y
P
D
D
I
V
S
N
Dog
Lupus familis
XP_534313
749
85531
Y481
A
I
K
E
R
I
G
Y
P
D
D
I
I
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61391
750
85683
Y482
A
I
K
E
R
I
G
Y
P
D
D
I
I
S
N
Rat
Rattus norvegicus
P07861
750
85777
Y482
A
I
K
E
R
I
G
Y
P
D
D
I
I
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001004412
750
85321
Y482
A
I
K
E
R
I
G
Y
P
D
E
I
M
T
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
P487
I
S
E
Q
I
G
Y
P
D
H
I
L
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
G582
D
S
M
N
E
R
I
G
Y
P
E
L
L
T
N
Honey Bee
Apis mellifera
XP_392502
776
89056
G509
N
S
M
N
E
R
I
G
Y
P
E
F
L
K
D
Nematode Worm
Caenorhab. elegans
O16796
848
97043
Y580
S
M
I
N
N
I
G
Y
P
D
V
T
N
D
L
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
G497
D
A
M
Q
E
L
V
G
Y
P
D
W
L
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.9
93
N.A.
94.1
94.2
N.A.
N.A.
78.8
N.A.
56.2
N.A.
36.2
39.9
32.9
38.6
Protein Similarity:
100
99.7
99.5
97
N.A.
97.7
97.8
N.A.
N.A.
88.8
N.A.
74.5
N.A.
53.9
59.2
52.1
59.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
73.3
N.A.
0
N.A.
6.6
0
33.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
20
N.A.
33.3
20
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
0
0
0
9
67
59
0
0
9
25
% D
% Glu:
0
0
9
59
25
0
0
0
0
0
25
0
9
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
0
0
0
0
0
9
67
25
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
59
9
0
9
67
17
0
0
0
9
59
25
0
0
% I
% Lys:
0
0
59
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
0
17
25
0
9
% L
% Met:
0
9
25
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
0
0
25
9
0
0
0
0
0
0
0
9
0
59
% N
% Pro:
0
0
0
0
0
0
0
9
67
25
0
0
0
0
0
% P
% Gln:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
59
17
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
25
0
0
0
0
0
0
0
0
0
0
0
50
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
0
17
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
9
0
25
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
67
25
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _