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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHA1
All Species:
44.55
Human Site:
Y65
Identified Species:
75.38
UniProt:
P08559
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08559
NP_000275.1
390
43296
Y65
R
E
D
G
L
K
Y
Y
R
M
M
Q
T
V
R
Chimpanzee
Pan troglodytes
A5A6L0
390
43219
Y65
R
E
D
G
L
K
Y
Y
R
M
M
Q
T
V
R
Rhesus Macaque
Macaca mulatta
XP_001097880
420
46631
Y95
R
A
E
G
L
K
Y
Y
R
M
M
L
T
V
R
Dog
Lupus familis
XP_537975
390
43375
Y65
R
E
D
G
L
R
Y
Y
R
M
M
Q
T
V
R
Cat
Felis silvestris
Mouse
Mus musculus
P35486
390
43213
Y65
R
E
D
G
L
K
Y
Y
R
M
M
Q
T
V
R
Rat
Rattus norvegicus
P26284
390
43208
Y65
R
E
D
G
L
K
Y
Y
R
M
M
Q
T
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514100
568
62886
Y243
R
E
E
G
L
K
Y
Y
R
T
M
Q
T
I
R
Chicken
Gallus gallus
NP_001012562
399
44424
Y72
R
E
E
G
L
H
Y
Y
K
T
M
Q
T
I
R
Frog
Xenopus laevis
NP_001087610
400
44764
Y75
R
E
E
G
L
Q
Y
Y
R
T
M
Q
T
I
R
Zebra Danio
Brachydanio rerio
NP_998558
393
43722
Y68
R
E
E
G
L
Q
Y
Y
R
T
M
Q
T
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52899
397
43773
I65
Y
Y
R
D
M
Q
V
I
R
R
M
E
S
A
A
Sea Urchin
Strong. purpuratus
XP_001175746
386
42313
Y63
K
D
E
A
L
D
Y
Y
H
K
M
Q
T
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P52901
389
43041
F63
S
Q
E
L
L
D
F
F
R
T
M
A
L
M
R
Baker's Yeast
Sacchar. cerevisiae
P16387
420
46325
Y85
K
A
T
L
L
Q
M
Y
K
D
M
V
I
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
79
98.9
N.A.
98.2
97.9
N.A.
63.7
84.7
82
80.1
N.A.
N.A.
N.A.
58.9
59.7
Protein Similarity:
100
99.7
85
99.7
N.A.
99.4
99.2
N.A.
67
91.2
92.2
90
N.A.
N.A.
N.A.
71.7
74.1
P-Site Identity:
100
100
80
93.3
N.A.
100
100
N.A.
80
66.6
73.3
73.3
N.A.
N.A.
N.A.
13.3
46.6
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
93.3
86.6
93.3
93.3
N.A.
N.A.
N.A.
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.9
46.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66.4
63.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
0
0
0
0
0
0
0
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
36
8
0
15
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
65
50
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
72
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
8
36
0
% I
% Lys:
15
0
0
0
0
43
0
0
15
8
0
0
0
0
0
% K
% Leu:
0
0
0
15
93
0
0
0
0
0
0
8
8
0
0
% L
% Met:
0
0
0
0
8
0
8
0
0
43
100
0
0
15
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
29
0
0
0
0
0
72
0
0
0
% Q
% Arg:
72
0
8
0
0
8
0
0
79
8
0
0
0
0
93
% R
% Ser:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
36
0
0
79
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
8
0
43
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
79
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _