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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYC1
All Species:
44.85
Human Site:
S312
Identified Species:
75.9
UniProt:
P08574
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08574
NP_001907.2
325
35390
S312
T
I
K
R
H
K
W
S
V
L
K
S
R
K
L
Chimpanzee
Pan troglodytes
XP_528263
468
49840
S455
T
I
K
R
H
K
W
S
V
L
K
S
R
K
L
Rhesus Macaque
Macaca mulatta
XP_001089897
325
35233
S312
I
M
K
R
H
K
W
S
V
L
K
S
R
K
L
Dog
Lupus familis
XP_532351
325
35262
S312
A
M
K
R
H
K
W
S
V
L
K
S
R
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0M3
325
35309
S312
A
M
K
R
H
K
W
S
V
L
K
S
R
K
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089640
309
34087
S296
Y
M
K
R
H
R
W
S
V
L
K
S
R
K
I
Zebra Danio
Brachydanio rerio
NP_001032470
307
33696
S294
Y
I
K
R
H
K
W
S
V
L
K
S
R
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647958
307
33746
S293
Y
I
K
R
H
K
W
S
S
L
K
S
R
K
I
Honey Bee
Apis mellifera
XP_397047
311
34926
T294
Y
W
K
R
H
K
W
T
T
V
K
N
T
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791551
304
33536
S290
Y
T
K
R
H
K
W
S
V
L
K
S
R
K
L
Poplar Tree
Populus trichocarpa
XP_002313590
310
33861
S297
Y
Y
R
R
L
K
W
S
V
L
K
S
R
K
L
Maize
Zea mays
NP_001141284
326
35416
S313
A
M
K
R
H
K
W
S
V
L
K
S
R
K
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07143
309
34036
A293
W
V
K
K
F
K
W
A
G
I
K
T
R
K
F
Red Bread Mold
Neurospora crassa
P07142
332
36438
A302
Y
V
K
R
Y
K
W
A
W
L
K
S
R
K
I
Conservation
Percent
Protein Identity:
100
69.4
94.7
92.3
N.A.
90.7
N.A.
N.A.
N.A.
N.A.
70.4
69.5
N.A.
55
52.9
N.A.
58.4
Protein Similarity:
100
69.4
97.5
94.4
N.A.
94.1
N.A.
N.A.
N.A.
N.A.
82.7
81.8
N.A.
69.8
70.1
N.A.
74.1
P-Site Identity:
100
100
86.6
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
73.3
86.6
N.A.
80
46.6
N.A.
86.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
93.3
93.3
N.A.
86.6
73.3
N.A.
86.6
Percent
Protein Identity:
50.7
90.4
N.A.
N.A.
48
48.4
Protein Similarity:
66.4
93.5
N.A.
N.A.
64.3
61.7
P-Site Identity:
73.3
86.6
N.A.
N.A.
40
60
P-Site Similarity:
80
93.3
N.A.
N.A.
73.3
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
79
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
29
0
0
0
0
0
0
0
8
0
0
0
0
36
% I
% Lys:
0
0
93
8
0
93
0
0
0
0
100
0
0
100
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
86
0
0
0
0
58
% L
% Met:
0
36
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
93
0
8
0
0
0
0
0
0
93
0
0
% R
% Ser:
0
0
0
0
0
0
0
79
8
0
0
86
0
0
0
% S
% Thr:
15
8
0
0
0
0
0
8
8
0
0
8
8
0
0
% T
% Val:
0
15
0
0
0
0
0
0
72
8
0
0
0
0
0
% V
% Trp:
8
8
0
0
0
0
100
0
8
0
0
0
0
0
0
% W
% Tyr:
50
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _