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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYC1
All Species:
26.36
Human Site:
Y94
Identified Species:
44.62
UniProt:
P08574
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08574
NP_001907.2
325
35390
Y94
L
E
L
H
P
P
S
Y
P
W
S
H
R
G
L
Chimpanzee
Pan troglodytes
XP_528263
468
49840
Y237
L
E
L
H
P
P
S
Y
P
W
S
H
R
G
L
Rhesus Macaque
Macaca mulatta
XP_001089897
325
35233
Y94
L
E
L
H
P
P
S
Y
P
W
S
H
S
G
F
Dog
Lupus familis
XP_532351
325
35262
Y94
L
E
L
H
P
P
S
Y
P
W
S
H
R
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0M3
325
35309
Y94
L
E
L
H
P
P
S
Y
P
W
S
H
R
G
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089640
309
34087
R96
L
D
H
A
S
I
R
R
G
Y
Q
V
Y
K
Q
Zebra Danio
Brachydanio rerio
NP_001032470
307
33696
R94
L
D
H
A
S
V
R
R
G
Y
Q
V
Y
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647958
307
33746
R93
L
D
H
Q
S
V
R
R
G
Y
E
V
Y
K
Q
Honey Bee
Apis mellifera
XP_397047
311
34926
R94
L
D
H
R
S
L
R
R
G
W
E
V
Y
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791551
304
33536
R90
F
D
H
A
S
L
R
R
G
Y
Q
V
Y
K
E
Poplar Tree
Populus trichocarpa
XP_002313590
310
33861
S94
L
S
S
Y
D
H
S
S
I
R
R
G
Q
Q
V
Maize
Zea mays
NP_001141284
326
35416
Y95
L
E
L
H
P
P
S
Y
P
W
S
H
R
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07143
309
34036
S89
F
E
T
F
D
H
A
S
I
R
R
G
Y
Q
V
Red Bread Mold
Neurospora crassa
P07142
332
36438
Y83
E
G
L
H
A
T
K
Y
P
W
V
H
E
Q
W
Conservation
Percent
Protein Identity:
100
69.4
94.7
92.3
N.A.
90.7
N.A.
N.A.
N.A.
N.A.
70.4
69.5
N.A.
55
52.9
N.A.
58.4
Protein Similarity:
100
69.4
97.5
94.4
N.A.
94.1
N.A.
N.A.
N.A.
N.A.
82.7
81.8
N.A.
69.8
70.1
N.A.
74.1
P-Site Identity:
100
100
86.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
6.6
6.6
N.A.
6.6
13.3
N.A.
0
P-Site Similarity:
100
100
86.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
20
20
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
50.7
90.4
N.A.
N.A.
48
48.4
Protein Similarity:
66.4
93.5
N.A.
N.A.
64.3
61.7
P-Site Identity:
13.3
100
N.A.
N.A.
6.6
40
P-Site Similarity:
33.3
100
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
22
8
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
36
0
0
15
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
50
0
0
0
0
0
0
0
0
15
0
8
0
8
% E
% Phe:
15
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
0
0
0
36
0
0
15
0
43
0
% G
% His:
0
0
36
50
0
15
0
0
0
0
0
50
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
15
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
36
0
% K
% Leu:
79
0
50
0
0
15
0
0
0
0
0
0
0
0
36
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
43
43
0
0
50
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
22
0
8
22
22
% Q
% Arg:
0
0
0
8
0
0
36
36
0
15
15
0
36
0
0
% R
% Ser:
0
8
8
0
36
0
50
15
0
0
43
0
8
0
0
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
15
0
0
0
0
8
36
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
58
0
0
0
0
8
% W
% Tyr:
0
0
0
8
0
0
0
50
0
29
0
0
43
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _