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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFI2
All Species:
10.61
Human Site:
S194
Identified Species:
23.33
UniProt:
P08582
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08582
NP_005920.2
738
80242
S194
R
L
C
R
G
D
S
S
G
E
G
V
C
D
K
Chimpanzee
Pan troglodytes
A5A6I6
698
77045
L201
P
G
C
G
C
S
T
L
N
Q
Y
F
G
Y
S
Rhesus Macaque
Macaca mulatta
XP_001096034
1540
163697
S347
R
L
C
R
G
D
S
S
G
E
G
V
C
D
K
Dog
Lupus familis
XP_545158
1193
127001
A331
R
Q
C
R
G
D
A
A
G
D
G
V
C
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0R1
738
81275
S194
R
L
C
R
G
D
S
S
G
H
N
V
C
D
K
Rat
Rattus norvegicus
P12346
698
76377
T201
P
G
C
G
C
S
P
T
Q
P
F
F
G
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512738
1031
113197
A270
Q
L
C
I
G
D
A
A
G
E
G
K
C
Y
K
Chicken
Gallus gallus
P02789
705
77758
K198
R
Q
C
K
G
D
P
K
T
K
C
A
R
N
A
Frog
Xenopus laevis
Q6PGT3
701
76838
H198
Q
C
A
G
K
K
E
H
K
C
S
R
S
N
N
Zebra Danio
Brachydanio rerio
Q0VIL3
371
40757
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786179
738
79097
S193
K
Q
C
P
A
D
S
S
E
L
Y
Q
S
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41
43.9
51.7
N.A.
83.7
39.4
N.A.
54.7
38.8
40.5
22.8
N.A.
N.A.
N.A.
N.A.
41.3
Protein Similarity:
100
57.9
45.4
56.8
N.A.
89.8
55.6
N.A.
62.9
54.8
57.5
33.2
N.A.
N.A.
N.A.
N.A.
56.7
P-Site Identity:
100
6.6
100
73.3
N.A.
86.6
6.6
N.A.
60
26.6
0
0
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
20
100
93.3
N.A.
86.6
13.3
N.A.
80
46.6
13.3
0
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
19
19
0
0
0
10
0
0
19
% A
% Cys:
0
10
82
0
19
0
0
0
0
10
10
0
46
0
0
% C
% Asp:
0
0
0
0
0
64
0
0
0
10
0
0
0
37
0
% D
% Glu:
0
0
0
0
0
0
10
0
10
28
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
19
0
0
0
% F
% Gly:
0
19
0
28
55
0
0
0
46
0
37
0
19
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
10
10
0
10
10
10
0
10
0
0
46
% K
% Leu:
0
37
0
0
0
0
0
10
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
10
0
0
19
10
% N
% Pro:
19
0
0
10
0
0
19
0
0
10
0
0
0
0
0
% P
% Gln:
19
28
0
0
0
0
0
0
10
10
0
10
0
0
0
% Q
% Arg:
46
0
0
37
0
0
0
0
0
0
0
10
10
0
0
% R
% Ser:
0
0
0
0
0
19
37
37
0
0
10
0
19
0
10
% S
% Thr:
0
0
0
0
0
0
10
10
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
37
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
19
0
0
37
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _