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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MFI2 All Species: 12.73
Human Site: S308 Identified Species: 28
UniProt: P08582 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08582 NP_005920.2 738 80242 S308 R L F S H E G S S F Q M F S S
Chimpanzee Pan troglodytes A5A6I6 698 77045 G309 Q L F S S P H G K D L L F K D
Rhesus Macaque Macaca mulatta XP_001096034 1540 163697 S461 R L F S H E G S S F Q M F S S
Dog Lupus familis XP_545158 1193 127001 S445 R L F S Q E G S S F Q M F S S
Cat Felis silvestris
Mouse Mus musculus Q9R0R1 738 81275 S308 L L F S H E D S S F Q M F S S
Rat Rattus norvegicus P12346 698 76377 G309 Q L F G S P L G K D L L F K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512738 1031 113197 A384 L R F N R K D A S F Q M F E S
Chicken Gallus gallus P02789 705 77758 H302 V D T K S D F H L F G P P G K
Frog Xenopus laevis Q6PGT3 701 76838 A309 D L I F K N S A V S L I P L P
Zebra Danio Brachydanio rerio Q0VIL3 371 40757 L12 G G H L A V V L F L F V L V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786179 738 79097 N302 F G D D N N Q N G F L M F D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41 43.9 51.7 N.A. 83.7 39.4 N.A. 54.7 38.8 40.5 22.8 N.A. N.A. N.A. N.A. 41.3
Protein Similarity: 100 57.9 45.4 56.8 N.A. 89.8 55.6 N.A. 62.9 54.8 57.5 33.2 N.A. N.A. N.A. N.A. 56.7
P-Site Identity: 100 26.6 100 93.3 N.A. 86.6 20 N.A. 46.6 6.6 6.6 6.6 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 40 100 93.3 N.A. 86.6 33.3 N.A. 66.6 13.3 20 13.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 19 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 10 10 0 10 19 0 0 19 0 0 0 10 19 % D
% Glu: 0 0 0 0 0 37 0 0 0 0 0 0 0 10 0 % E
% Phe: 10 0 64 10 0 0 10 0 10 64 10 0 73 0 0 % F
% Gly: 10 19 0 10 0 0 28 19 10 0 10 0 0 10 0 % G
% His: 0 0 10 0 28 0 10 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 10 10 10 0 0 19 0 0 0 0 19 10 % K
% Leu: 19 64 0 10 0 0 10 10 10 10 37 19 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 % M
% Asn: 0 0 0 10 10 19 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 19 0 0 0 0 0 10 19 0 10 % P
% Gln: 19 0 0 0 10 0 10 0 0 0 46 0 0 0 0 % Q
% Arg: 28 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 46 28 0 10 37 46 10 0 0 0 37 64 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 10 10 0 10 0 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _