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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFI2
All Species:
20.61
Human Site:
S315
Identified Species:
45.33
UniProt:
P08582
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08582
NP_005920.2
738
80242
S315
S
S
F
Q
M
F
S
S
E
A
Y
G
Q
K
D
Chimpanzee
Pan troglodytes
A5A6I6
698
77045
D316
G
K
D
L
L
F
K
D
S
A
H
G
F
L
K
Rhesus Macaque
Macaca mulatta
XP_001096034
1540
163697
S468
S
S
F
Q
M
F
S
S
E
A
Y
G
Q
K
D
Dog
Lupus familis
XP_545158
1193
127001
S452
S
S
F
Q
M
F
S
S
E
A
Y
G
Q
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0R1
738
81275
S315
S
S
F
Q
M
F
S
S
K
A
Y
S
Q
K
N
Rat
Rattus norvegicus
P12346
698
76377
D316
G
K
D
L
L
F
K
D
S
A
F
G
L
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512738
1031
113197
S391
A
S
F
Q
M
F
E
S
G
A
Y
L
Q
K
N
Chicken
Gallus gallus
P02789
705
77758
K309
H
L
F
G
P
P
G
K
K
D
P
V
L
K
D
Frog
Xenopus laevis
Q6PGT3
701
76838
P316
A
V
S
L
I
P
L
P
P
S
M
D
G
F
L
Zebra Danio
Brachydanio rerio
Q0VIL3
371
40757
S19
L
F
L
F
V
L
V
S
M
S
T
E
N
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786179
738
79097
S309
N
G
F
L
M
F
D
S
V
A
Y
G
G
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41
43.9
51.7
N.A.
83.7
39.4
N.A.
54.7
38.8
40.5
22.8
N.A.
N.A.
N.A.
N.A.
41.3
Protein Similarity:
100
57.9
45.4
56.8
N.A.
89.8
55.6
N.A.
62.9
54.8
57.5
33.2
N.A.
N.A.
N.A.
N.A.
56.7
P-Site Identity:
100
20
100
93.3
N.A.
80
20
N.A.
66.6
20
0
6.6
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
33.3
100
100
N.A.
93.3
33.3
N.A.
80
26.6
20
20
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
0
0
73
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
0
10
19
0
10
0
10
0
0
37
% D
% Glu:
0
0
0
0
0
0
10
0
28
0
0
10
0
0
0
% E
% Phe:
0
10
64
10
0
73
0
0
0
0
10
0
10
10
0
% F
% Gly:
19
10
0
10
0
0
10
0
10
0
0
55
19
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
19
0
0
0
0
19
10
19
0
0
0
0
55
10
% K
% Leu:
10
10
10
37
19
10
10
0
0
0
0
10
19
19
10
% L
% Met:
0
0
0
0
55
0
0
0
10
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
10
19
28
% N
% Pro:
0
0
0
0
10
19
0
10
10
0
10
0
0
0
0
% P
% Gln:
0
0
0
46
0
0
0
0
0
0
0
0
46
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
37
46
10
0
0
0
37
64
19
19
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
10
0
0
10
0
10
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
55
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _