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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFI2
All Species:
22.12
Human Site:
T466
Identified Species:
48.67
UniProt:
P08582
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08582
NP_005920.2
738
80242
T466
R
D
S
S
H
A
F
T
L
D
E
L
R
G
K
Chimpanzee
Pan troglodytes
A5A6I6
698
77045
T459
K
K
S
A
S
D
L
T
W
D
N
L
K
G
K
Rhesus Macaque
Macaca mulatta
XP_001096034
1540
163697
T619
R
D
S
S
H
A
F
T
L
D
E
L
R
G
K
Dog
Lupus familis
XP_545158
1193
127001
S603
R
N
S
S
D
A
F
S
L
D
E
L
R
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0R1
738
81275
T466
R
D
S
S
Y
S
F
T
L
D
E
L
R
G
K
Rat
Rattus norvegicus
P12346
698
76377
N461
K
A
S
D
S
S
I
N
W
N
N
L
K
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512738
1031
113197
T542
K
D
S
T
N
A
F
T
I
N
D
L
Q
G
K
Chicken
Gallus gallus
P02789
705
77758
N465
K
D
S
N
V
N
W
N
N
L
K
G
K
K
S
Frog
Xenopus laevis
Q6PGT3
701
76838
S454
A
K
K
G
T
K
V
S
W
S
N
L
R
G
V
Zebra Danio
Brachydanio rerio
Q0VIL3
371
40757
T155
P
I
G
F
L
V
N
T
S
Q
I
S
V
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786179
738
79097
G455
A
R
K
G
T
Q
F
G
M
D
D
L
A
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41
43.9
51.7
N.A.
83.7
39.4
N.A.
54.7
38.8
40.5
22.8
N.A.
N.A.
N.A.
N.A.
41.3
Protein Similarity:
100
57.9
45.4
56.8
N.A.
89.8
55.6
N.A.
62.9
54.8
57.5
33.2
N.A.
N.A.
N.A.
N.A.
56.7
P-Site Identity:
100
40
100
73.3
N.A.
86.6
26.6
N.A.
53.3
13.3
20
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
60
100
93.3
N.A.
100
53.3
N.A.
100
46.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
10
0
37
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
0
10
10
10
0
0
0
55
19
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
55
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
19
0
0
0
10
0
0
0
10
0
82
0
% G
% His:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
10
0
10
0
10
0
0
0
0
% I
% Lys:
37
19
19
0
0
10
0
0
0
0
10
0
28
10
55
% K
% Leu:
0
0
0
0
10
0
10
0
37
10
0
82
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
10
10
19
10
19
28
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
10
0
0
10
0
0
% Q
% Arg:
37
10
0
0
0
0
0
0
0
0
0
0
46
0
19
% R
% Ser:
0
0
73
37
19
19
0
19
10
10
0
10
0
0
10
% S
% Thr:
0
0
0
10
19
0
0
55
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
10
10
0
0
0
0
0
10
0
19
% V
% Trp:
0
0
0
0
0
0
10
0
28
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _