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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFI2
All Species:
14.85
Human Site:
Y426
Identified Species:
32.67
UniProt:
P08582
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08582
NP_005920.2
738
80242
Y426
T
L
S
G
E
D
I
Y
T
A
G
K
K
Y
G
Chimpanzee
Pan troglodytes
A5A6I6
698
77045
G419
G
G
F
V
Y
I
A
G
K
C
G
L
V
P
V
Rhesus Macaque
Macaca mulatta
XP_001096034
1540
163697
Y579
T
L
S
G
E
D
I
Y
T
A
G
K
T
Y
G
Dog
Lupus familis
XP_545158
1193
127001
Y563
T
L
R
G
E
D
T
Y
L
A
G
Q
K
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0R1
738
81275
Y426
T
L
R
G
E
D
I
Y
R
A
G
K
V
Y
G
Rat
Rattus norvegicus
P12346
698
76377
G421
A
Y
I
A
G
Q
C
G
L
V
P
V
M
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512738
1031
113197
Y502
T
L
G
G
G
D
I
Y
V
A
G
K
T
Y
G
Chicken
Gallus gallus
P02789
705
77758
G425
V
Y
T
A
G
V
C
G
L
V
P
V
M
A
E
Frog
Xenopus laevis
Q6PGT3
701
76838
L414
Y
T
A
G
Q
C
G
L
V
P
V
M
G
E
Y
Zebra Danio
Brachydanio rerio
Q0VIL3
371
40757
A115
G
I
N
Y
Y
V
V
A
L
A
R
T
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786179
738
79097
D415
V
V
T
L
D
G
G
D
L
Y
A
G
G
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41
43.9
51.7
N.A.
83.7
39.4
N.A.
54.7
38.8
40.5
22.8
N.A.
N.A.
N.A.
N.A.
41.3
Protein Similarity:
100
57.9
45.4
56.8
N.A.
89.8
55.6
N.A.
62.9
54.8
57.5
33.2
N.A.
N.A.
N.A.
N.A.
56.7
P-Site Identity:
100
6.6
93.3
66.6
N.A.
80
0
N.A.
73.3
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
93.3
80
N.A.
80
0
N.A.
73.3
6.6
20
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
19
0
0
10
10
0
55
10
0
0
19
0
% A
% Cys:
0
0
0
0
0
10
19
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
46
0
10
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
37
0
0
0
0
0
0
0
0
10
19
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
10
55
28
10
19
28
0
0
55
10
19
0
46
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
10
0
0
10
37
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
37
19
0
0
% K
% Leu:
0
46
0
10
0
0
0
10
46
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
19
0
0
10
0
% P
% Gln:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
19
0
0
0
0
0
10
0
10
0
0
0
10
% R
% Ser:
0
0
19
0
0
0
0
0
0
0
0
0
10
10
10
% S
% Thr:
46
10
19
0
0
0
10
0
19
0
0
10
19
0
0
% T
% Val:
19
10
0
10
0
19
10
0
19
19
10
19
19
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
19
0
10
19
0
0
46
0
10
0
0
0
37
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _