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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFI2
All Species:
18.18
Human Site:
Y451
Identified Species:
40
UniProt:
P08582
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08582
NP_005920.2
738
80242
Y451
P
E
D
S
S
N
S
Y
Y
V
V
A
V
V
R
Chimpanzee
Pan troglodytes
A5A6I6
698
77045
G444
C
E
D
T
P
E
A
G
Y
F
A
V
A
V
V
Rhesus Macaque
Macaca mulatta
XP_001096034
1540
163697
Y604
S
E
D
S
S
N
S
Y
F
V
V
A
V
V
R
Dog
Lupus familis
XP_545158
1193
127001
Y588
P
D
D
T
S
S
S
Y
F
A
V
A
V
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0R1
738
81275
Y451
E
E
D
R
S
N
S
Y
F
V
V
A
V
A
R
Rat
Rattus norvegicus
P12346
698
76377
G446
Q
S
D
V
F
P
K
G
Y
Y
A
V
A
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512738
1031
113197
Y527
E
S
D
R
S
N
S
Y
Y
A
V
A
V
V
K
Chicken
Gallus gallus
P02789
705
77758
Y450
T
D
E
R
P
A
S
Y
F
A
V
A
V
A
R
Frog
Xenopus laevis
Q6PGT3
701
76838
G439
R
R
S
S
G
T
K
G
V
Y
Y
A
V
A
I
Zebra Danio
Brachydanio rerio
Q0VIL3
371
40757
R140
S
S
C
H
P
G
M
R
T
T
V
G
W
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786179
738
79097
A440
V
G
G
D
N
P
D
A
S
Y
W
A
V
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41
43.9
51.7
N.A.
83.7
39.4
N.A.
54.7
38.8
40.5
22.8
N.A.
N.A.
N.A.
N.A.
41.3
Protein Similarity:
100
57.9
45.4
56.8
N.A.
89.8
55.6
N.A.
62.9
54.8
57.5
33.2
N.A.
N.A.
N.A.
N.A.
56.7
P-Site Identity:
100
26.6
86.6
60
N.A.
73.3
20
N.A.
66.6
40
20
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
40
93.3
93.3
N.A.
80
20
N.A.
73.3
60
20
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
10
0
28
19
73
19
37
0
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
64
10
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
19
37
10
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
37
10
0
0
0
0
0
% F
% Gly:
0
10
10
0
10
10
0
28
0
0
0
10
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% I
% Lys:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
19
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
37
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
0
0
0
28
19
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
28
0
0
0
10
0
0
0
0
0
0
37
% R
% Ser:
19
28
10
28
46
10
55
0
10
0
0
0
0
0
0
% S
% Thr:
10
0
0
19
0
10
0
0
10
10
0
0
0
10
0
% T
% Val:
10
0
0
10
0
0
0
0
10
28
64
19
73
55
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
37
28
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _