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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFI2
All Species:
18.48
Human Site:
Y527
Identified Species:
40.67
UniProt:
P08582
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08582
NP_005920.2
738
80242
Y527
P
V
N
N
P
K
N
Y
P
S
S
L
C
A
L
Chimpanzee
Pan troglodytes
A5A6I6
698
77045
S511
A
P
G
S
K
K
D
S
S
L
C
K
L
C
M
Rhesus Macaque
Macaca mulatta
XP_001096034
1540
163697
Y680
P
V
N
N
P
K
N
Y
P
S
S
L
C
A
L
Dog
Lupus familis
XP_545158
1193
127001
Y664
P
V
N
N
P
Q
N
Y
P
G
S
L
C
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0R1
738
81275
Y527
P
V
N
N
P
K
N
Y
P
S
A
L
C
A
L
Rat
Rattus norvegicus
P12346
698
76377
K511
G
C
A
P
G
Y
K
K
N
S
T
L
C
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512738
1031
113197
Y603
P
V
N
N
A
E
D
Y
P
A
S
L
C
E
L
Chicken
Gallus gallus
P02789
705
77758
R516
P
G
S
P
P
N
S
R
L
C
Q
L
C
Q
G
Frog
Xenopus laevis
Q6PGT3
701
76838
K507
P
G
S
D
V
K
S
K
L
C
A
L
C
I
G
Zebra Danio
Brachydanio rerio
Q0VIL3
371
40757
E205
C
E
A
C
I
G
D
E
N
D
R
H
I
C
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786179
738
79097
N524
K
Y
D
P
T
G
T
N
P
S
S
L
C
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41
43.9
51.7
N.A.
83.7
39.4
N.A.
54.7
38.8
40.5
22.8
N.A.
N.A.
N.A.
N.A.
41.3
Protein Similarity:
100
57.9
45.4
56.8
N.A.
89.8
55.6
N.A.
62.9
54.8
57.5
33.2
N.A.
N.A.
N.A.
N.A.
56.7
P-Site Identity:
100
6.6
100
86.6
N.A.
93.3
26.6
N.A.
66.6
26.6
26.6
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
33.3
N.A.
86.6
40
53.3
6.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
0
10
0
0
0
0
10
19
0
0
46
10
% A
% Cys:
10
10
0
10
0
0
0
0
0
19
10
0
82
19
0
% C
% Asp:
0
0
10
10
0
0
28
0
0
10
0
0
0
10
0
% D
% Glu:
0
10
0
0
0
10
0
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
19
10
0
10
19
0
0
0
10
0
0
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
10
10
0
% I
% Lys:
10
0
0
0
10
46
10
19
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
19
10
0
82
10
0
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
46
46
0
10
37
10
19
0
0
0
0
0
0
% N
% Pro:
64
10
0
28
46
0
0
0
55
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
10
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% R
% Ser:
0
0
19
10
0
0
19
10
10
46
46
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% T
% Val:
0
46
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _