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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFI2
All Species:
15.76
Human Site:
Y99
Identified Species:
34.67
UniProt:
P08582
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08582
NP_005920.2
738
80242
Y99
K
P
V
V
G
E
V
Y
D
Q
E
V
G
T
S
Chimpanzee
Pan troglodytes
A5A6I6
698
77045
S106
V
V
A
E
F
Y
G
S
K
E
D
P
Q
T
F
Rhesus Macaque
Macaca mulatta
XP_001096034
1540
163697
W252
H
P
I
I
G
P
Q
W
G
Q
E
V
G
T
S
Dog
Lupus familis
XP_545158
1193
127001
Y236
K
P
V
V
G
E
V
Y
D
Q
E
V
G
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0R1
738
81275
Y99
K
P
V
V
G
E
V
Y
D
Q
D
I
G
T
S
Rat
Rattus norvegicus
P12346
698
76377
S106
V
A
A
E
F
Y
G
S
L
E
H
P
Q
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512738
1031
113197
Y175
K
P
V
V
G
E
V
Y
D
Q
E
V
G
T
S
Chicken
Gallus gallus
P02789
705
77758
H103
I
A
A
E
V
Y
E
H
T
E
G
S
T
T
S
Frog
Xenopus laevis
Q6PGT3
701
76838
S103
I
M
A
E
N
Y
G
S
Q
T
E
T
D
T
C
Zebra Danio
Brachydanio rerio
Q0VIL3
371
40757
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786179
738
79097
V98
D
R
Y
A
G
I
A
V
V
R
A
T
D
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41
43.9
51.7
N.A.
83.7
39.4
N.A.
54.7
38.8
40.5
22.8
N.A.
N.A.
N.A.
N.A.
41.3
Protein Similarity:
100
57.9
45.4
56.8
N.A.
89.8
55.6
N.A.
62.9
54.8
57.5
33.2
N.A.
N.A.
N.A.
N.A.
56.7
P-Site Identity:
100
6.6
53.3
100
N.A.
86.6
6.6
N.A.
100
13.3
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
73.3
100
N.A.
100
13.3
N.A.
100
26.6
13.3
0
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
37
10
0
0
10
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
0
0
0
0
37
0
19
0
19
0
0
% D
% Glu:
0
0
0
37
0
37
10
0
0
28
46
0
0
0
0
% E
% Phe:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
55
0
28
0
10
0
10
0
46
0
0
% G
% His:
10
0
0
0
0
0
0
10
0
0
10
0
0
0
10
% H
% Ile:
19
0
10
10
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
37
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
46
0
0
0
10
0
0
0
0
0
19
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
10
46
0
0
19
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
28
0
0
0
10
0
10
55
% S
% Thr:
0
0
0
0
0
0
0
0
10
10
0
19
10
82
10
% T
% Val:
19
10
37
37
10
0
37
10
10
0
0
37
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
37
0
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _