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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRB1
All Species:
14.24
Human Site:
S312
Identified Species:
31.33
UniProt:
P08588
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08588
NP_000675.1
477
51323
S312
R
A
G
K
R
R
P
S
R
L
V
A
L
R
E
Chimpanzee
Pan troglodytes
XP_521608
476
51237
S311
R
A
G
K
R
R
P
S
R
L
V
A
L
R
E
Rhesus Macaque
Macaca mulatta
P47899
480
51591
S315
R
A
G
K
R
R
P
S
R
L
V
A
L
R
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P34971
466
50461
K310
L
V
A
L
R
E
Q
K
A
L
K
T
L
G
I
Rat
Rattus norvegicus
P18090
466
50453
K310
L
V
A
L
R
E
Q
K
A
L
K
T
L
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513543
477
52086
S319
R
P
G
K
R
R
P
S
R
L
L
A
L
K
E
Chicken
Gallus gallus
XP_428541
514
55555
P362
T
F
T
L
C
W
L
P
F
F
V
A
N
I
I
Frog
Xenopus laevis
O42574
385
43291
R253
S
H
V
L
S
H
G
R
S
S
R
R
I
L
S
Zebra Danio
Brachydanio rerio
NP_001122161
390
43773
K258
I
L
A
L
K
E
Q
K
A
L
K
T
L
G
I
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
T311
F
P
C
I
S
S
T
T
F
D
V
F
V
W
F
Fruit Fly
Dros. melanogaster
Q4LBB9
536
60360
I401
P
T
K
D
K
H
L
I
K
M
K
R
E
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.5
N.A.
N.A.
90.9
90.7
N.A.
72.7
51.3
53.8
52.4
26.4
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
97.5
N.A.
N.A.
91.8
91.8
N.A.
78.8
63.8
64.7
64.7
43.1
45.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
20
20
N.A.
80
13.3
0
13.3
6.6
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
20
20
N.A.
93.3
13.3
6.6
20
20
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
28
28
0
0
0
0
0
28
0
0
46
0
0
0
% A
% Cys:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
28
0
0
0
0
0
0
10
0
37
% E
% Phe:
10
10
0
0
0
0
0
0
19
10
0
10
0
0
10
% F
% Gly:
0
0
37
0
0
0
10
0
0
0
0
0
0
28
0
% G
% His:
0
10
0
0
0
19
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
10
0
0
0
10
0
0
0
0
10
10
37
% I
% Lys:
0
0
10
37
19
0
0
28
10
0
37
0
0
10
10
% K
% Leu:
19
10
0
46
0
0
19
0
0
64
10
0
64
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
19
0
0
0
0
37
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% Q
% Arg:
37
0
0
0
55
37
0
10
37
0
10
19
0
28
0
% R
% Ser:
10
0
0
0
19
10
0
37
10
10
0
0
0
0
10
% S
% Thr:
10
10
10
0
0
0
10
10
0
0
0
28
0
0
0
% T
% Val:
0
19
10
0
0
0
0
0
0
0
46
0
10
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _