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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYL3
All Species:
30.91
Human Site:
Y130
Identified Species:
68
UniProt:
P08590
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08590
NP_000249.1
195
21932
Y130
K
N
K
D
T
G
T
Y
E
D
F
V
E
G
L
Chimpanzee
Pan troglodytes
XP_511623
193
21196
Y128
R
N
K
D
Q
G
T
Y
E
D
F
V
E
G
L
Rhesus Macaque
Macaca mulatta
XP_001113910
196
21941
Y131
K
N
K
D
T
G
T
Y
E
D
F
V
E
G
L
Dog
Lupus familis
XP_533849
201
22351
Y136
K
N
K
D
T
G
T
Y
E
D
F
V
E
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P09542
204
22403
Y139
K
N
K
D
T
G
T
Y
E
D
F
V
E
G
L
Rat
Rattus norvegicus
P16409
200
22138
Y135
K
N
K
D
T
G
T
Y
E
D
F
V
E
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02606
194
21978
Y129
K
T
K
D
T
G
T
Y
E
D
F
V
E
G
L
Frog
Xenopus laevis
NP_001079225
190
21167
Y125
K
N
K
D
Q
G
S
Y
E
D
F
V
E
G
L
Zebra Danio
Brachydanio rerio
XP_001921730
187
20941
F122
R
S
K
D
Q
G
T
F
E
D
F
V
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54357
147
16595
F85
S
G
D
T
A
D
D
F
I
E
G
L
R
H
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P53014
153
17126
V91
D
F
Y
E
G
L
K
V
F
D
K
E
E
T
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81
95.9
92.5
N.A.
92.6
94
N.A.
N.A.
81.5
77.9
77.4
N.A.
38.9
N.A.
35.9
N.A.
Protein Similarity:
100
88.2
96.9
95.5
N.A.
94.6
95.5
N.A.
N.A.
89.7
86.1
86.6
N.A.
55.3
N.A.
50.2
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
73.3
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
82
0
10
10
0
0
91
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
82
10
0
10
91
0
0
% E
% Phe:
0
10
0
0
0
0
0
19
10
0
82
0
0
0
10
% F
% Gly:
0
10
0
0
10
82
0
0
0
0
10
0
0
82
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
64
0
82
0
0
0
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
82
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
64
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
28
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
10
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
10
55
0
73
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
82
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _