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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGF4 All Species: 26.36
Human Site: Y169 Identified Species: 72.5
UniProt: P08620 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08620 NP_001998.1 206 22048 Y169 L P N N Y N A Y E S Y K Y P G
Chimpanzee Pan troglodytes XP_001157123 208 22895 Y171 L P N N Y N A Y E S D L Y R G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540801 206 21985 Y169 L P N N Y N A Y E C Y R Y P G
Cat Felis silvestris
Mouse Mus musculus P11403 202 21884 Y165 L P N N Y N A Y E A Y A Y P G
Rat Rattus norvegicus P48807 266 29246 Y172 Q E N S Y N T Y A S A I H R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506743 192 21708 Y155 L P N N Y N A Y E S R S Y P G
Chicken Gallus gallus P48804 194 21624 Y157 L P N N Y N A Y E S R I Y P G
Frog Xenopus laevis P48806 192 21885 Y155 L P N N Y N A Y E S R K Y P G
Zebra Danio Brachydanio rerio Q6PBT8 147 16619 N111 Q S Q K Y G E N W Y V G I K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.8 N.A. 92.7 N.A. 79.6 31.2 N.A. 68.4 66.9 60.1 30.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 65.3 N.A. 95.1 N.A. 85.4 42.4 N.A. 78.6 76.2 72.8 42.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 80 N.A. 86.6 N.A. 86.6 33.3 N.A. 86.6 86.6 93.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 N.A. 93.3 N.A. 93.3 46.6 N.A. 86.6 86.6 93.3 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 78 0 12 12 12 12 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % D
% Glu: 0 12 0 0 0 0 12 0 78 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 12 0 0 0 0 0 12 0 0 78 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 23 12 0 0 % I
% Lys: 0 0 0 12 0 0 0 0 0 0 0 23 0 12 12 % K
% Leu: 78 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 89 78 0 89 0 12 0 0 0 0 0 0 0 % N
% Pro: 0 78 0 0 0 0 0 0 0 0 0 0 0 67 0 % P
% Gln: 23 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 34 12 0 23 0 % R
% Ser: 0 12 0 12 0 0 0 0 0 67 0 12 0 0 0 % S
% Thr: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 12 % T
% Val: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 100 0 0 89 0 12 34 0 78 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _