Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SNRNP70 All Species: 22.73
Human Site: S257 Identified Species: 35.71
UniProt: P08621 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08621 NP_003080.2 437 51557 S257 K E R E R R R S R S R D R R R
Chimpanzee Pan troglodytes XP_001156213 534 62599 S354 K E R E R R R S R S R D R R R
Rhesus Macaque Macaca mulatta XP_001112732 579 66665 S399 K E R E R R R S R S R D R R R
Dog Lupus familis XP_541503 439 51493 S257 K E R E R R R S R S R D R R R
Cat Felis silvestris
Mouse Mus musculus Q62376 448 51974 S257 K E R E R R R S R S R D R R R
Rat Rattus norvegicus Q5U1W5 244 29185 I117 R D A D G L V I D Q H E I F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517310 232 27182 T104 A Q G D A F K T L F V A R V N
Chicken Gallus gallus
Frog Xenopus laevis P09406 471 57185 S261 E R R R K S R S R E K E E R K
Zebra Danio Brachydanio rerio Q4KMD3 208 24569 L81 G D I R R L R L V R D V V T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17133 448 52882 A293 R E R R K R R A G S R E R Y D
Honey Bee Apis mellifera XP_623789 450 53998 R264 R D R K R R T R S R S R D R K
Nematode Worm Caenorhab. elegans Q10021 208 23961 R81 G K P R G N D R H G S R S P R
Sea Urchin Strong. purpuratus XP_001193416 500 59344 D318 R D R D R E R D R G G R R D R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42404 427 50370 E288 L S H E Q P R E R S R D R P R
Baker's Yeast Sacchar. cerevisiae Q00916 300 34429 G173 K E I G V H R G I Q I K D R I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.8 75.4 98.4 N.A. 95.3 27.9 N.A. 51.9 N.A. 67.5 23.7 N.A. 42.4 46.6 24.4 50
Protein Similarity: 100 81.8 75.4 98.8 N.A. 96.4 37 N.A. 52.6 N.A. 76.6 31.5 N.A. 57.1 59.7 32.7 61.6
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 6.6 N.A. 33.3 13.3 N.A. 46.6 26.6 6.6 40
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 33.3 N.A. 66.6 20 N.A. 73.3 53.3 13.3 60
Percent
Protein Identity: N.A. N.A. N.A. 39.8 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. 56.7 37 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 7 0 0 7 0 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 27 0 20 0 0 7 7 7 0 7 40 14 7 7 % D
% Glu: 7 47 0 40 0 7 0 7 0 7 0 20 7 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 7 0 0 0 7 0 % F
% Gly: 14 0 7 7 14 0 0 7 7 14 7 0 0 0 7 % G
% His: 0 0 7 0 0 7 0 0 7 0 7 0 0 0 0 % H
% Ile: 0 0 14 0 0 0 0 7 7 0 7 0 7 0 7 % I
% Lys: 40 7 0 7 14 0 7 0 0 0 7 7 0 0 14 % K
% Leu: 7 0 0 0 0 14 0 7 7 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 0 7 0 0 7 0 0 0 0 0 0 0 14 0 % P
% Gln: 0 7 0 0 7 0 0 0 0 14 0 0 0 0 0 % Q
% Arg: 27 7 60 27 54 47 74 14 54 14 47 20 60 54 54 % R
% Ser: 0 7 0 0 0 7 0 40 7 47 14 0 7 0 0 % S
% Thr: 0 0 0 0 0 0 7 7 0 0 0 0 0 7 0 % T
% Val: 0 0 0 0 7 0 7 0 7 0 7 7 7 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _