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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGA5
All Species:
23.64
Human Site:
S395
Identified Species:
47.27
UniProt:
P08648
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08648
NP_002196.2
1049
114536
S395
E
F
G
R
F
G
S
S
L
T
P
L
G
D
L
Chimpanzee
Pan troglodytes
XP_515967
1243
136876
A568
V
F
A
R
F
G
S
A
I
A
P
L
G
D
L
Rhesus Macaque
Macaca mulatta
XP_001110116
1050
114818
S395
E
F
G
R
F
G
S
S
L
T
P
L
G
D
L
Dog
Lupus familis
XP_543619
1077
117515
S421
E
F
G
R
F
G
S
S
L
T
P
L
G
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P11688
1053
115038
S398
E
F
S
R
F
G
S
S
L
T
P
L
G
D
L
Rat
Rattus norvegicus
Q63258
1135
124176
S384
P
D
S
M
F
G
I
S
L
A
V
L
G
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508582
998
109248
E372
V
R
P
S
Q
I
L
E
G
A
W
T
S
E
T
Chicken
Gallus gallus
P26009
1044
116123
A371
V
F
G
R
F
G
S
A
I
T
H
L
G
D
L
Frog
Xenopus laevis
Q06274
1050
115944
S384
E
Y
G
R
F
G
S
S
I
A
S
L
G
D
L
Zebra Danio
Brachydanio rerio
NP_001004288
1035
114737
S364
M
F
A
R
F
G
S
S
I
T
P
L
G
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12080
1396
154303
A403
S
K
G
R
F
G
L
A
L
T
T
L
G
D
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34446
1226
135921
A379
Q
W
G
R
F
G
H
A
V
A
A
A
G
D
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.9
96
85.2
N.A.
90.2
28.1
N.A.
44
46.2
64.3
55.6
N.A.
26.2
N.A.
29.1
N.A.
Protein Similarity:
100
56.7
96.8
89.3
N.A.
95
43.9
N.A.
61.4
66.2
76.7
71.4
N.A.
43.9
N.A.
45.8
N.A.
P-Site Identity:
100
66.6
100
100
N.A.
93.3
53.3
N.A.
0
73.3
73.3
80
N.A.
60
N.A.
46.6
N.A.
P-Site Similarity:
100
80
100
100
N.A.
93.3
53.3
N.A.
6.6
86.6
86.6
86.6
N.A.
73.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
34
0
42
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
0
92
0
% D
% Glu:
42
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% E
% Phe:
0
59
0
0
92
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
59
0
0
92
0
0
9
0
0
0
92
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
34
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
17
0
50
0
0
84
0
0
84
% L
% Met:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
9
0
0
0
0
0
0
0
50
0
0
0
0
% P
% Gln:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
84
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
17
9
0
0
67
59
0
0
9
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
59
9
9
0
0
9
% T
% Val:
25
0
0
0
0
0
0
0
9
0
9
0
0
0
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _