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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITGA5 All Species: 23.94
Human Site: S742 Identified Species: 47.88
UniProt: P08648 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08648 NP_002196.2 1049 114536 S742 N P M K A G A S L W G G L R F
Chimpanzee Pan troglodytes XP_515967 1243 136876 Q917 N P M K A G T Q L L A G L R F
Rhesus Macaque Macaca mulatta XP_001110116 1050 114818 S743 N P M K A G A S L W G G L R F
Dog Lupus familis XP_543619 1077 117515 S768 N P M K A G A S I W G G L R F
Cat Felis silvestris
Mouse Mus musculus P11688 1053 115038 S745 N P M K A G T S L W G G L R F
Rat Rattus norvegicus Q63258 1135 124176 G756 L G N P M K R G T Q V T F Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508582 998 109248 S700 F D L H I R S S N Q D H P Q S
Chicken Gallus gallus P26009 1044 116123 N719 N P M V A G A N F S T G I R F
Frog Xenopus laevis Q06274 1050 115944 S732 N P M K A G A S L A G G L R F
Zebra Danio Brachydanio rerio NP_001004288 1035 114737 S718 N P M K S G T S L W A G L R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P12080 1396 154303 I757 N P L E S G K I A H F K I S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34446 1226 135921 S752 P A N K V V S S V V R V T A S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.9 96 85.2 N.A. 90.2 28.1 N.A. 44 46.2 64.3 55.6 N.A. 26.2 N.A. 29.1 N.A.
Protein Similarity: 100 56.7 96.8 89.3 N.A. 95 43.9 N.A. 61.4 66.2 76.7 71.4 N.A. 43.9 N.A. 45.8 N.A.
P-Site Identity: 100 73.3 100 93.3 N.A. 93.3 0 N.A. 6.6 60 93.3 80 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 73.3 100 100 N.A. 93.3 0 N.A. 26.6 73.3 93.3 86.6 N.A. 46.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 59 0 42 0 9 9 17 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 9 0 9 0 9 0 67 % F
% Gly: 0 9 0 0 0 75 0 9 0 0 42 67 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 9 0 9 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 9 9 0 0 0 17 0 0 % I
% Lys: 0 0 0 67 0 9 9 0 0 0 0 9 0 0 0 % K
% Leu: 9 0 17 0 0 0 0 0 50 9 0 0 59 0 17 % L
% Met: 0 0 67 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 75 0 17 0 0 0 0 9 9 0 0 0 0 0 0 % N
% Pro: 9 75 0 9 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 17 0 0 0 9 0 % Q
% Arg: 0 0 0 0 0 9 9 0 0 0 9 0 0 67 0 % R
% Ser: 0 0 0 0 17 0 17 67 0 9 0 0 0 9 17 % S
% Thr: 0 0 0 0 0 0 25 0 9 0 9 9 9 0 0 % T
% Val: 0 0 0 9 9 9 0 0 9 9 9 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 42 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _