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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP21A2
All Species:
20.3
Human Site:
S113
Identified Species:
44.67
UniProt:
P08686
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08686
NP_000491
494
55887
S113
D
L
S
L
G
D
Y
S
L
L
W
K
A
H
K
Chimpanzee
Pan troglodytes
Q8HYN1
508
57365
G118
G
I
A
F
A
D
S
G
A
H
W
Q
L
H
R
Rhesus Macaque
Macaca mulatta
Q8HYM9
508
57600
G118
G
I
A
F
A
D
Y
G
A
H
W
Q
L
H
R
Dog
Lupus familis
XP_855593
492
55347
S113
D
L
S
L
G
D
Y
S
L
L
W
K
A
H
K
Cat
Felis silvestris
Mouse
Mus musculus
P03940
487
55309
S110
D
L
S
L
G
D
Y
S
L
M
W
K
A
H
K
Rat
Rattus norvegicus
Q64562
493
55927
S112
D
L
S
M
G
D
Y
S
L
T
W
K
A
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P12394
508
56966
G123
D
I
A
F
A
S
Y
G
P
L
W
K
F
Q
R
Frog
Xenopus laevis
NP_001087443
370
41973
H62
D
P
D
F
Q
K
I
H
K
C
I
I
D
I
I
Zebra Danio
Brachydanio rerio
XP_001919231
534
59970
S152
T
I
S
L
G
D
F
S
E
E
W
K
A
H
R
Tiger Blowfish
Takifugu rubipres
NP_001098706
517
57319
S124
D
I
A
F
G
D
Y
S
A
T
W
R
F
H
R
Fruit Fly
Dros. melanogaster
Q95078
538
61930
K141
N
S
T
G
K
L
W
K
D
Q
R
R
F
L
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.2
31.2
77.9
N.A.
71.2
69.6
N.A.
N.A.
36
32.1
39.3
33.8
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
51.5
51.9
86.8
N.A.
81.7
80.9
N.A.
N.A.
54.1
47.1
55.4
50.4
45.5
N.A.
N.A.
N.A.
P-Site Identity:
100
20
26.6
100
N.A.
93.3
86.6
N.A.
N.A.
33.3
6.6
60
46.6
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
53.3
100
N.A.
100
93.3
N.A.
N.A.
53.3
6.6
80
73.3
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
37
0
28
0
0
0
28
0
0
0
46
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
64
0
10
0
0
73
0
0
10
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
46
0
0
10
0
0
0
0
0
28
0
0
% F
% Gly:
19
0
0
10
55
0
0
28
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
19
0
0
0
73
10
% H
% Ile:
0
46
0
0
0
0
10
0
0
0
10
10
0
10
10
% I
% Lys:
0
0
0
0
10
10
0
10
10
0
0
55
0
0
37
% K
% Leu:
0
37
0
37
0
10
0
0
37
28
0
0
19
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
19
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
19
0
0
46
% R
% Ser:
0
10
46
0
0
10
10
55
0
0
0
0
0
0
0
% S
% Thr:
10
0
10
0
0
0
0
0
0
19
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
82
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
64
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _