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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F7 All Species: 14.55
Human Site: S399 Identified Species: 32
UniProt: P08709 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08709 NP_000122.1 466 51594 S399 Y S D G S K D S C K G D S G G
Chimpanzee Pan troglodytes Q2F9P2 466 51600 S399 Y S D G S K D S C K G D S G G
Rhesus Macaque Macaca mulatta NP_001073605 472 52443 S405 Y S D G S R D S C K G D S G G
Dog Lupus familis XP_534191 486 53473 A419 Y D S K P E D A C Q G D S G G
Cat Felis silvestris
Mouse Mus musculus P70375 446 50258 A380 Y M D G T K D A C K G D S G G
Rat Rattus norvegicus Q8K3U6 446 50381 A380 Y M D G T K D A C K G D S G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001121086 469 52177 N398 S S F D I T P N M F C A G Y D
Chicken Gallus gallus P25155 475 53123 T395 V P Y V D R S T C K Q S T N F
Frog Xenopus laevis NP_001085965 432 48865 G370 F C A G F T D G S K D S C K G
Zebra Danio Brachydanio rerio NP_001083027 431 47757 A367 V S R N M L C A G F A E G G R
Tiger Blowfish Takifugu rubipres NP_001027863 441 49311 S374 Y M E G R Q D S C K G D S G G
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 90 40.1 N.A. 66.9 65.8 N.A. 42.6 42.3 50.8 44.2 41.8 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 93.2 58.8 N.A. 77.6 76.1 N.A. 60.1 60 65.8 60.2 58.3 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 53.3 N.A. 80 80 N.A. 6.6 13.3 26.6 13.3 73.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 73.3 N.A. 93.3 93.3 N.A. 13.3 33.3 33.3 26.6 86.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 37 0 0 10 10 0 0 0 % A
% Cys: 0 10 0 0 0 0 10 0 73 0 10 0 10 0 0 % C
% Asp: 0 10 46 10 10 0 73 0 0 0 10 64 0 0 10 % D
% Glu: 0 0 10 0 0 10 0 0 0 0 0 10 0 0 0 % E
% Phe: 10 0 10 0 10 0 0 0 0 19 0 0 0 0 10 % F
% Gly: 0 0 0 64 0 0 0 10 10 0 64 0 19 73 73 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 37 0 0 0 73 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % L
% Met: 0 28 0 0 10 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 10 0 0 0 0 0 10 0 % N
% Pro: 0 10 0 0 10 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 10 10 0 0 0 0 % Q
% Arg: 0 0 10 0 10 19 0 0 0 0 0 0 0 0 10 % R
% Ser: 10 46 10 0 28 0 10 37 10 0 0 19 64 0 0 % S
% Thr: 0 0 0 0 19 19 0 10 0 0 0 0 10 0 0 % T
% Val: 19 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 64 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _