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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F7 All Species: 20
Human Site: Y412 Identified Species: 44
UniProt: P08709 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08709 NP_000122.1 466 51594 Y412 G G P H A T H Y R G T W Y L T
Chimpanzee Pan troglodytes Q2F9P2 466 51600 Y412 G G P H A T H Y R G T W Y L T
Rhesus Macaque Macaca mulatta NP_001073605 472 52443 Y418 G G P H A T R Y R G T W Y L T
Dog Lupus familis XP_534191 486 53473 F432 G G P H V T R F K D T Y F V T
Cat Felis silvestris
Mouse Mus musculus P70375 446 50258 Y393 G G P H A T H Y H G T W Y L T
Rat Rattus norvegicus Q8K3U6 446 50381 Y393 G G P H A T H Y H G T W Y L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001121086 469 52177 A411 Y D S R P E D A C Q G D S G G
Chicken Gallus gallus P25155 475 53123 M408 N F A I T E N M F C A G Y E T
Frog Xenopus laevis NP_001085965 432 48865 H383 K G D S G G P H A T E Y K N T
Zebra Danio Brachydanio rerio NP_001083027 431 47757 D380 G R D S C Q G D S G G P L V T
Tiger Blowfish Takifugu rubipres NP_001027863 441 49311 Y387 G G P L V T K Y K K T V F L L
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 90 40.1 N.A. 66.9 65.8 N.A. 42.6 42.3 50.8 44.2 41.8 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 93.2 58.8 N.A. 77.6 76.1 N.A. 60.1 60 65.8 60.2 58.3 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 46.6 N.A. 93.3 93.3 N.A. 0 13.3 13.3 20 46.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 80 N.A. 93.3 93.3 N.A. 0 20 26.6 26.6 60 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 46 0 0 10 10 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 10 10 0 0 0 0 0 % C
% Asp: 0 10 19 0 0 0 10 10 0 10 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 19 0 0 0 0 10 0 0 10 0 % E
% Phe: 0 10 0 0 0 0 0 10 10 0 0 0 19 0 0 % F
% Gly: 73 73 0 0 10 10 10 0 0 55 19 10 0 10 10 % G
% His: 0 0 0 55 0 0 37 10 19 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 10 0 19 10 0 0 10 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 0 0 10 55 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 64 0 10 0 10 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 10 0 10 0 0 19 0 28 0 0 0 0 0 0 % R
% Ser: 0 0 10 19 0 0 0 0 10 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 10 64 0 0 0 10 64 0 0 0 82 % T
% Val: 0 0 0 0 19 0 0 0 0 0 0 10 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 46 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 55 0 0 0 19 55 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _