KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STS
All Species:
26.06
Human Site:
Y445
Identified Species:
63.7
UniProt:
P08842
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08842
NP_000342.2
583
65492
Y445
D
H
E
F
L
F
H
Y
C
N
A
Y
L
N
A
Chimpanzee
Pan troglodytes
XP_520918
590
66235
Y452
D
H
E
F
L
F
H
Y
C
N
A
Y
L
N
A
Rhesus Macaque
Macaca mulatta
XP_001088752
590
66331
Y452
D
H
E
F
L
F
H
Y
C
N
A
Y
L
N
A
Dog
Lupus familis
XP_548847
617
67857
Y440
D
H
E
F
L
F
H
Y
C
N
F
Y
L
N
A
Cat
Felis silvestris
Mouse
Mus musculus
P50427
624
66572
H452
S
E
H
E
F
L
F
H
Y
C
N
A
Y
L
Q
Rat
Rattus norvegicus
P15589
577
62660
H432
L
M
P
L
L
L
G
H
V
Q
H
S
E
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514842
673
75646
Y530
E
H
E
F
L
F
H
Y
C
N
A
Y
L
N
A
Chicken
Gallus gallus
XP_416850
588
66130
Y447
K
H
E
F
L
F
H
Y
C
N
A
Y
L
N
A
Frog
Xenopus laevis
NP_001086084
586
65282
Y447
E
H
E
F
L
Y
H
Y
C
G
P
H
L
H
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P50473
567
62459
D422
D
F
F
Y
Y
C
K
D
T
L
M
A
V
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
95.5
74.3
N.A.
54.8
62.6
N.A.
62.4
65.4
50.1
N.A.
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
98.4
97.8
83.6
N.A.
67.6
75.1
N.A.
74.5
80.6
64.5
N.A.
N.A.
N.A.
N.A.
N.A.
41.5
P-Site Identity:
100
100
100
93.3
N.A.
0
6.6
N.A.
93.3
93.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
6.6
20
N.A.
100
93.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
50
20
0
0
70
% A
% Cys:
0
0
0
0
0
10
0
0
70
10
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
20
10
70
10
0
0
0
0
0
0
0
0
10
0
10
% E
% Phe:
0
10
10
70
10
60
10
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% G
% His:
0
70
10
0
0
0
70
20
0
0
10
10
0
20
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
10
80
20
0
0
0
10
0
0
70
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
60
10
0
0
60
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
10
0
70
10
0
0
60
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _