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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD63 All Species: 14.55
Human Site: S159 Identified Species: 29.09
UniProt: P08962 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08962 NP_001771.1 238 25637 S159 T D W E K I P S M S K N R V P
Chimpanzee Pan troglodytes Q7YQL0 244 26954 Y159 T N W S T S P Y F L E H G I P
Rhesus Macaque Macaca mulatta XP_001111129 215 23411 S136 T D W E K I P S M S K N R V P
Dog Lupus familis XP_531624 238 25596 L159 T D W Q T V S L M P K G Q V P
Cat Felis silvestris
Mouse Mus musculus P41731 238 25748 G159 T D W E N I P G M A K D R V P
Rat Rattus norvegicus P28648 238 25680 G159 T D W E R I P G M A K D R V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416779 249 27590 Y164 T N W S T S P Y F F K H G I P
Frog Xenopus laevis Q6GQF5 268 29872 S178 N C S S E N R S Q E R C S V P
Zebra Danio Brachydanio rerio Q5RH71 281 31706 S177 N C S D D N P S R E R C S V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625099 236 25796 N191 I H S N G C M N N L Q S A I E
Nematode Worm Caenorhab. elegans NP_492636 232 25188 T158 S D W L T F T T I P D S C C I
Sea Urchin Strong. purpuratus XP_800780 239 26205 M158 T D W M G Y N M S H P D M V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 30.7 90.3 89.9 N.A. 79.4 78.5 N.A. N.A. 30.9 27.9 26.6 N.A. N.A. 39 32.7 35.9
Protein Similarity: 100 52.8 90.3 93.6 N.A. 88.2 88.2 N.A. N.A. 53 49.2 50.8 N.A. N.A. 55.4 52 57.3
P-Site Identity: 100 26.6 100 46.6 N.A. 73.3 73.3 N.A. N.A. 33.3 20 26.6 N.A. N.A. 0 13.3 33.3
P-Site Similarity: 100 53.3 100 66.6 N.A. 86.6 93.3 N.A. N.A. 53.3 33.3 40 N.A. N.A. 26.6 40 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 17 0 0 9 0 0 % A
% Cys: 0 17 0 0 0 9 0 0 0 0 0 17 9 9 0 % C
% Asp: 0 59 0 9 9 0 0 0 0 0 9 25 0 0 0 % D
% Glu: 0 0 0 34 9 0 0 0 0 17 9 0 0 0 9 % E
% Phe: 0 0 0 0 0 9 0 0 17 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 17 0 0 17 0 0 0 9 17 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 9 0 17 0 0 0 % H
% Ile: 9 0 0 0 0 34 0 0 9 0 0 0 0 25 9 % I
% Lys: 0 0 0 0 17 0 0 0 0 0 50 0 0 0 0 % K
% Leu: 0 0 0 9 0 0 0 9 0 17 0 0 0 0 0 % L
% Met: 0 0 0 9 0 0 9 9 42 0 0 0 9 0 0 % M
% Asn: 17 17 0 9 9 17 9 9 9 0 0 17 0 0 0 % N
% Pro: 0 0 0 0 0 0 59 0 0 17 9 0 0 0 84 % P
% Gln: 0 0 0 9 0 0 0 0 9 0 9 0 9 0 0 % Q
% Arg: 0 0 0 0 9 0 9 0 9 0 17 0 34 0 0 % R
% Ser: 9 0 25 25 0 17 9 34 9 17 0 17 17 0 0 % S
% Thr: 67 0 0 0 34 0 9 9 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 0 0 67 0 % V
% Trp: 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 17 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _