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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD63 All Species: 29.09
Human Site: Y126 Identified Species: 58.18
UniProt: P08962 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08962 NP_001771.1 238 25637 Y126 F R Q Q M E N Y P K N N H T A
Chimpanzee Pan troglodytes Q7YQL0 244 26954 Y126 Y T D A M Q T Y N G N D E R S
Rhesus Macaque Macaca mulatta XP_001111129 215 23411 Y103 F R Q Q M E N Y P K N N H T A
Dog Lupus familis XP_531624 238 25596 Y126 F R E Q M K N Y Q K N N H T A
Cat Felis silvestris
Mouse Mus musculus P41731 238 25748 Y126 F Q Q Q M Q N Y L K D N K T A
Rat Rattus norvegicus P28648 238 25680 Y126 F Q K Q M Q N Y L T D N K T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416779 249 27590 Y131 Y T E A I Q N Y N K N D E R S
Frog Xenopus laevis Q6GQF5 268 29872 Y136 I S N A I E H Y R D D L D L Q
Zebra Danio Brachydanio rerio Q5RH71 281 31706 Y135 F D N A I K H Y R D D L D L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625099 236 25796 Y125 L N I T M E E Y T T N D D I H
Nematode Worm Caenorhab. elegans NP_492636 232 25188 Y125 L Q T G M V R Y H E S R G V E
Sea Urchin Strong. purpuratus XP_800780 239 26205 Y125 M T D L Q K E Y N S S T S T Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 30.7 90.3 89.9 N.A. 79.4 78.5 N.A. N.A. 30.9 27.9 26.6 N.A. N.A. 39 32.7 35.9
Protein Similarity: 100 52.8 90.3 93.6 N.A. 88.2 88.2 N.A. N.A. 53 49.2 50.8 N.A. N.A. 55.4 52 57.3
P-Site Identity: 100 20 100 80 N.A. 66.6 53.3 N.A. N.A. 26.6 13.3 13.3 N.A. N.A. 26.6 13.3 13.3
P-Site Similarity: 100 46.6 100 93.3 N.A. 86.6 80 N.A. N.A. 66.6 33.3 40 N.A. N.A. 33.3 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 42 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 17 0 0 0 0 0 0 17 34 25 25 0 0 % D
% Glu: 0 0 17 0 0 34 17 0 0 9 0 0 17 0 9 % E
% Phe: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 9 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 17 0 9 0 0 0 25 0 9 % H
% Ile: 9 0 9 0 25 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 9 0 0 25 0 0 0 42 0 0 17 0 0 % K
% Leu: 17 0 0 9 0 0 0 0 17 0 0 17 0 17 0 % L
% Met: 9 0 0 0 67 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 17 0 0 0 50 0 25 0 50 42 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % P
% Gln: 0 25 25 42 9 34 0 0 9 0 0 0 0 0 25 % Q
% Arg: 0 25 0 0 0 0 9 0 17 0 0 9 0 17 0 % R
% Ser: 0 9 0 0 0 0 0 0 0 9 17 0 9 0 17 % S
% Thr: 0 25 9 9 0 0 9 0 9 17 0 9 0 50 0 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _