Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HOXD4 All Species: 13.03
Human Site: S222 Identified Species: 23.89
UniProt: P09016 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09016 NP_055436.2 255 27885 S222 L P N T K G R S S S S S S S S
Chimpanzee Pan troglodytes NP_001075038 255 27817 S222 L P N T K G R S S S S S S S S
Rhesus Macaque Macaca mulatta XP_001094862 255 27890 S222 L P N T K G R S S S S S S S S
Dog Lupus familis XP_543624 264 29776 S224 L P N T K V R S A P P A G A A
Cat Felis silvestris
Mouse Mus musculus P10628 250 27352 K217 D H K L P N T K G R S S S S S
Rat Rattus norvegicus P18865 76 9274 I44 T R R R R I E I A H S L C L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516048 239 27107 H207 R M K W K K D H K L P N T K G
Chicken Gallus gallus P17278 235 26643 H203 R M K W K K D H K L P N T K G
Frog Xenopus laevis P09070 232 26449 H200 R M K W K K D H K L P N T K I
Zebra Danio Brachydanio rerio O57374 236 27114 D204 R R M K W K K D H K L P N T K
Tiger Blowfish Takifugu rubipres Q1KKS8 233 26734 T201 Q N R R M K W T K D H K L P N
Fruit Fly Dros. melanogaster P07548 586 63362 L522 Y P G S Q Q H L S N N N N N G
Honey Bee Apis mellifera P15860 74 9244 A42 R R R R I E I A H A L C L T E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 52.2 N.A. 92.1 26.2 N.A. 75.2 71.7 47.4 60.3 62.3 26.6 23.1 N.A. N.A.
Protein Similarity: 100 99.2 96.8 62.8 N.A. 92.5 28.6 N.A. 80 77.6 57.6 68.2 69.4 32.4 27 N.A. N.A.
P-Site Identity: 100 100 100 46.6 N.A. 33.3 13.3 N.A. 6.6 6.6 6.6 0 0 13.3 0 N.A. N.A.
P-Site Similarity: 100 100 100 73.3 N.A. 33.3 26.6 N.A. 20 20 20 20 13.3 60 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 16 8 0 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % C
% Asp: 8 0 0 0 0 0 24 8 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 24 0 0 8 0 0 0 8 0 24 % G
% His: 0 8 0 0 0 0 8 24 16 8 8 0 0 0 0 % H
% Ile: 0 0 0 0 8 8 8 8 0 0 0 0 0 0 8 % I
% Lys: 0 0 31 8 54 39 8 8 31 8 0 8 0 24 8 % K
% Leu: 31 0 0 8 0 0 0 8 0 24 16 8 16 8 0 % L
% Met: 0 24 8 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 31 0 0 8 0 0 0 8 8 31 16 8 8 % N
% Pro: 0 39 0 0 8 0 0 0 0 8 31 8 0 8 0 % P
% Gln: 8 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 39 24 24 24 8 0 31 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 8 0 0 0 31 31 24 39 31 31 31 39 % S
% Thr: 8 0 0 31 0 0 8 8 0 0 0 0 24 16 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 24 8 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _