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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOXD4
All Species:
16.36
Human Site:
S227
Identified Species:
30
UniProt:
P09016
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09016
NP_055436.2
255
27885
S227
G
R
S
S
S
S
S
S
S
S
S
C
S
S
S
Chimpanzee
Pan troglodytes
NP_001075038
255
27817
S227
G
R
S
S
S
S
S
S
S
S
S
C
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001094862
255
27890
S227
G
R
S
S
S
S
S
S
S
S
S
C
S
S
S
Dog
Lupus familis
XP_543624
264
29776
G229
V
R
S
A
P
P
A
G
A
A
P
S
T
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P10628
250
27352
S222
N
T
K
G
R
S
S
S
S
S
S
C
S
S
S
Rat
Rattus norvegicus
P18865
76
9274
C49
I
E
I
A
H
S
L
C
L
S
E
R
Q
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516048
239
27107
T212
K
D
H
K
L
P
N
T
K
G
R
S
S
N
T
Chicken
Gallus gallus
P17278
235
26643
T208
K
D
H
K
L
P
N
T
K
G
R
S
S
S
S
Frog
Xenopus laevis
P09070
232
26449
T205
K
D
H
K
L
P
N
T
K
I
K
S
N
P
S
Zebra Danio
Brachydanio rerio
O57374
236
27114
N209
K
K
D
H
K
L
P
N
T
K
G
R
S
A
S
Tiger Blowfish
Takifugu rubipres
Q1KKS8
233
26734
L206
K
W
T
K
D
H
K
L
P
N
T
K
G
R
S
Fruit Fly
Dros. melanogaster
P07548
586
63362
N527
Q
H
L
S
N
N
N
N
N
G
S
G
N
N
N
Honey Bee
Apis mellifera
P15860
74
9244
L47
E
I
A
H
A
L
C
L
T
E
R
Q
I
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.4
52.2
N.A.
92.1
26.2
N.A.
75.2
71.7
47.4
60.3
62.3
26.6
23.1
N.A.
N.A.
Protein Similarity:
100
99.2
96.8
62.8
N.A.
92.5
28.6
N.A.
80
77.6
57.6
68.2
69.4
32.4
27
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
66.6
13.3
N.A.
6.6
20
6.6
13.3
6.6
13.3
0
N.A.
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
66.6
20
N.A.
33.3
33.3
26.6
40
26.6
66.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
8
0
8
0
8
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
31
0
0
0
% C
% Asp:
0
24
8
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
24
0
0
8
0
0
0
8
0
24
8
8
8
0
0
% G
% His:
0
8
24
16
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
0
0
0
0
0
0
8
0
0
8
8
8
% I
% Lys:
39
8
8
31
8
0
8
0
24
8
8
8
0
8
8
% K
% Leu:
0
0
8
0
24
16
8
16
8
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
8
31
16
8
8
0
0
16
16
8
% N
% Pro:
0
0
0
0
8
31
8
0
8
0
8
0
0
8
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
0
31
0
0
8
0
0
0
0
0
24
16
0
8
0
% R
% Ser:
0
0
31
31
24
39
31
31
31
39
39
31
54
39
70
% S
% Thr:
0
8
8
0
0
0
0
24
16
0
8
0
8
0
8
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _