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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HOXD4 All Species: 16.36
Human Site: S230 Identified Species: 30
UniProt: P09016 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09016 NP_055436.2 255 27885 S230 S S S S S S S S C S S S V A P
Chimpanzee Pan troglodytes NP_001075038 255 27817 S230 S S S S S S S S C S S S V A P
Rhesus Macaque Macaca mulatta XP_001094862 255 27890 S230 S S S S S S S S C S S S V T P
Dog Lupus familis XP_543624 264 29776 P232 A P P A G A A P S T L S A A T
Cat Felis silvestris
Mouse Mus musculus P10628 250 27352 S225 G R S S S S S S C S S S A A P
Rat Rattus norvegicus P18865 76 9274 E52 A H S L C L S E R Q I K I W F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516048 239 27107 R215 K L P N T K G R S S N T A S T
Chicken Gallus gallus P17278 235 26643 R211 K L P N T K G R S S S S A S N
Frog Xenopus laevis P09070 232 26449 K208 K L P N T K I K S N P S V N L
Zebra Danio Brachydanio rerio O57374 236 27114 G212 H K L P N T K G R S A S V G N
Tiger Blowfish Takifugu rubipres Q1KKS8 233 26734 T209 K D H K L P N T K G R S A P A
Fruit Fly Dros. melanogaster P07548 586 63362 S530 S N N N N N G S G N N N N N N
Honey Bee Apis mellifera P15860 74 9244 R50 H A L C L T E R Q I K I W F Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 52.2 N.A. 92.1 26.2 N.A. 75.2 71.7 47.4 60.3 62.3 26.6 23.1 N.A. N.A.
Protein Similarity: 100 99.2 96.8 62.8 N.A. 92.5 28.6 N.A. 80 77.6 57.6 68.2 69.4 32.4 27 N.A. N.A.
P-Site Identity: 100 100 93.3 13.3 N.A. 80 13.3 N.A. 6.6 20 13.3 20 6.6 13.3 0 N.A. N.A.
P-Site Similarity: 100 100 93.3 46.6 N.A. 80 26.6 N.A. 40 40 33.3 40 20 66.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 8 0 8 8 0 0 0 8 0 39 31 8 % A
% Cys: 0 0 0 8 8 0 0 0 31 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % F
% Gly: 8 0 0 0 8 0 24 8 8 8 0 0 0 8 0 % G
% His: 16 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 8 8 8 8 0 0 % I
% Lys: 31 8 0 8 0 24 8 8 8 0 8 8 0 0 0 % K
% Leu: 0 24 16 8 16 8 0 0 0 0 8 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 31 16 8 8 0 0 16 16 8 8 16 24 % N
% Pro: 0 8 31 8 0 8 0 8 0 0 8 0 0 8 31 % P
% Gln: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 8 % Q
% Arg: 0 8 0 0 0 0 0 24 16 0 8 0 0 0 0 % R
% Ser: 31 24 39 31 31 31 39 39 31 54 39 70 0 16 0 % S
% Thr: 0 0 0 0 24 16 0 8 0 8 0 8 0 8 16 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _