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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOXD4
All Species:
14.55
Human Site:
T218
Identified Species:
26.67
UniProt:
P09016
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09016
NP_055436.2
255
27885
T218
K
D
H
K
L
P
N
T
K
G
R
S
S
S
S
Chimpanzee
Pan troglodytes
NP_001075038
255
27817
T218
K
D
H
K
L
P
N
T
K
G
R
S
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001094862
255
27890
T218
K
D
H
K
L
P
N
T
K
G
R
S
S
S
S
Dog
Lupus familis
XP_543624
264
29776
T220
K
D
H
R
L
P
N
T
K
V
R
S
A
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P10628
250
27352
L213
K
W
K
K
D
H
K
L
P
N
T
K
G
R
S
Rat
Rattus norvegicus
P18865
76
9274
R40
N
R
Y
L
T
R
R
R
R
I
E
I
A
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516048
239
27107
W203
F
Q
N
R
R
M
K
W
K
K
D
H
K
L
P
Chicken
Gallus gallus
P17278
235
26643
W199
F
Q
N
R
R
M
K
W
K
K
D
H
K
L
P
Frog
Xenopus laevis
P09070
232
26449
W196
F
Q
N
R
R
M
K
W
K
K
D
H
K
L
P
Zebra Danio
Brachydanio rerio
O57374
236
27114
K200
W
F
Q
N
R
R
M
K
W
K
K
D
H
K
L
Tiger Blowfish
Takifugu rubipres
Q1KKS8
233
26734
R197
K
I
W
F
Q
N
R
R
M
K
W
T
K
D
H
Fruit Fly
Dros. melanogaster
P07548
586
63362
S518
T
T
S
S
Y
P
G
S
Q
Q
H
L
S
N
N
Honey Bee
Apis mellifera
P15860
74
9244
R38
R
Y
L
T
R
R
R
R
I
E
I
A
H
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.4
52.2
N.A.
92.1
26.2
N.A.
75.2
71.7
47.4
60.3
62.3
26.6
23.1
N.A.
N.A.
Protein Similarity:
100
99.2
96.8
62.8
N.A.
92.5
28.6
N.A.
80
77.6
57.6
68.2
69.4
32.4
27
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
20
6.6
N.A.
6.6
6.6
6.6
0
6.6
13.3
0
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
20
26.6
N.A.
20
20
20
6.6
13.3
40
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
8
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
31
0
0
8
0
0
0
0
0
24
8
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% E
% Phe:
24
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
24
0
0
8
0
0
% G
% His:
0
0
31
0
0
8
0
0
0
0
8
24
16
8
8
% H
% Ile:
0
8
0
0
0
0
0
0
8
8
8
8
0
0
0
% I
% Lys:
47
0
8
31
0
0
31
8
54
39
8
8
31
8
0
% K
% Leu:
0
0
8
8
31
0
0
8
0
0
0
8
0
24
16
% L
% Met:
0
0
0
0
0
24
8
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
24
8
0
8
31
0
0
8
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
39
0
0
8
0
0
0
0
8
31
% P
% Gln:
0
24
8
0
8
0
0
0
8
8
0
0
0
0
0
% Q
% Arg:
8
8
0
31
39
24
24
24
8
0
31
0
0
8
0
% R
% Ser:
0
0
8
8
0
0
0
8
0
0
0
31
31
24
39
% S
% Thr:
8
8
0
8
8
0
0
31
0
0
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
8
8
8
0
0
0
0
24
8
0
8
0
0
0
0
% W
% Tyr:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _