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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HOXC4 All Species: 14.85
Human Site: S249 Identified Species: 29.7
UniProt: P09017 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09017 NP_055435.2 264 29811 S249 T S E D H S Q S A T P P E Q Q
Chimpanzee Pan troglodytes NP_001075038 255 27817 H240 S S V A P S Q H L Q P M A K D
Rhesus Macaque Macaca mulatta XP_001094862 255 27890 H240 S S V T P G Q H L Q P M A K D
Dog Lupus familis XP_543624 264 29776 S249 T S E D H S Q S A T P P E Q Q
Cat Felis silvestris
Mouse Mus musculus Q08624 264 29847 S249 T S E D H S Q S A T P P E Q Q
Rat Rattus norvegicus NP_001103354 264 29817 S249 T S E D H S Q S A T P P E Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516048 239 27107 L225 N T A S T Q H L Q T L P K D H
Chicken Gallus gallus P14840 245 27764 P231 S A S L Q I P P A A S Q S R S
Frog Xenopus laevis P09070 232 26449 A218 P S V N L Q I A G G S P N Q N
Zebra Danio Brachydanio rerio Q9PWM3 268 30093 T247 V V A A A S T T N T M S A S E
Tiger Blowfish Takifugu rubipres Q1KKU6 264 29725 A248 A S A T N T G A P D E L T G A
Fruit Fly Dros. melanogaster P07548 586 63362 K459 T K R A A S K K Q Q Q A Q Q Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.8 52.2 99.2 N.A. 98.8 99.2 N.A. 57.2 59.4 50 70.1 68.9 26.7 N.A. N.A. N.A.
Protein Similarity: 100 62.5 63.2 99.6 N.A. 98.8 99.2 N.A. 68.9 72.3 60.9 78.7 78 32.9 N.A. N.A. N.A.
P-Site Identity: 100 26.6 20 100 N.A. 100 100 N.A. 13.3 6.6 20 13.3 6.6 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 40 33.3 100 N.A. 100 100 N.A. 26.6 26.6 33.3 26.6 26.6 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 25 25 17 0 0 17 42 9 0 9 25 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 34 0 0 0 0 0 9 0 0 0 9 17 % D
% Glu: 0 0 34 0 0 0 0 0 0 0 9 0 34 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 9 0 9 9 0 0 0 9 0 % G
% His: 0 0 0 0 34 0 9 17 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 0 9 9 0 0 0 0 9 17 0 % K
% Leu: 0 0 0 9 9 0 0 9 17 0 9 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 17 0 0 0 % M
% Asn: 9 0 0 9 9 0 0 0 9 0 0 0 9 0 9 % N
% Pro: 9 0 0 0 17 0 9 9 9 0 50 50 0 0 0 % P
% Gln: 0 0 0 0 9 17 50 0 17 25 9 9 9 50 42 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % R
% Ser: 25 67 9 9 0 59 0 34 0 0 17 9 9 9 9 % S
% Thr: 42 9 0 17 9 9 9 9 0 50 0 0 9 0 0 % T
% Val: 9 9 25 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _