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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGF2 All Species: 12.73
Human Site: T254 Identified Species: 31.11
UniProt: P09038 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09038 NP_001997.5 288 30770 T254 T Y R S R K Y T S W Y V A L K
Chimpanzee Pan troglodytes NP_001103711 288 30717 T254 T Y R S R K Y T S W Y V A L K
Rhesus Macaque Macaca mulatta XP_001099284 237 26362 T203 T Y R S R K Y T S W Y V A L K
Dog Lupus familis XP_849274 155 17432 W122 K K H A E K N W F V G L K K N
Cat Felis silvestris
Mouse Mus musculus P15655 154 17134 S121 Y R S R K Y S S W Y V A L K R
Rat Rattus norvegicus P13109 154 17120 S121 Y R S R K Y S S W Y V A L K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515996 175 19632 N142 Y Q S R K H S N W Y V A L K R
Chicken Gallus gallus P48800 158 17355 D125 Y R S R K Y S D W Y V A L K R
Frog Xenopus laevis P12226 155 17223 S122 Y R S R K Y S S W Y V A L K R
Zebra Danio Brachydanio rerio Q6PBT8 147 16619 V114 K Y G E N W Y V G I K K N G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 63.5 29.5 N.A. 51.7 52 N.A. 40.2 50.6 44.7 21.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 68.4 36.4 N.A. 53.1 53.4 N.A. 46.8 52.4 48.6 34 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 0 0 N.A. 0 0 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 26.6 26.6 N.A. 20 20 26.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 50 30 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 10 0 10 0 0 10 0 % G
% His: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 20 10 0 0 50 40 0 0 0 0 10 10 10 60 40 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 10 50 30 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 10 10 0 0 0 0 10 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 40 30 50 30 0 0 0 0 0 0 0 0 0 50 % R
% Ser: 0 0 50 30 0 0 50 30 30 0 0 0 0 0 0 % S
% Thr: 30 0 0 0 0 0 0 30 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 10 50 30 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 10 50 30 0 0 0 0 0 % W
% Tyr: 50 40 0 0 0 40 40 0 0 50 30 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _