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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGF2 All Species: 13.64
Human Site: Y253 Identified Species: 33.33
UniProt: P09038 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09038 NP_001997.5 288 30770 Y253 N T Y R S R K Y T S W Y V A L
Chimpanzee Pan troglodytes NP_001103711 288 30717 Y253 N T Y R S R K Y T S W Y V A L
Rhesus Macaque Macaca mulatta XP_001099284 237 26362 Y202 N T Y R S R K Y T S W Y V A L
Dog Lupus familis XP_849274 155 17432 N121 S K K H A E K N W F V G L K K
Cat Felis silvestris
Mouse Mus musculus P15655 154 17134 S120 T Y R S R K Y S S W Y V A L K
Rat Rattus norvegicus P13109 154 17120 S120 T Y R S R K Y S S W Y V A L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515996 175 19632 S141 T Y Q S R K H S N W Y V A L K
Chicken Gallus gallus P48800 158 17355 S124 T Y R S R K Y S D W Y V A L K
Frog Xenopus laevis P12226 155 17223 S121 T Y R S R K Y S S W Y V A L K
Zebra Danio Brachydanio rerio Q6PBT8 147 16619 Y113 Q K Y G E N W Y V G I K K N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 63.5 29.5 N.A. 51.7 52 N.A. 40.2 50.6 44.7 21.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 68.4 36.4 N.A. 53.1 53.4 N.A. 46.8 52.4 48.6 34 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 0 0 N.A. 0 0 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 20 20 N.A. 13.3 13.3 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 0 50 30 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 10 0 10 0 0 10 % G
% His: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 20 10 0 0 50 40 0 0 0 0 10 10 10 60 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 10 50 30 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 30 0 0 0 0 10 0 10 10 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 40 30 50 30 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 50 30 0 0 50 30 30 0 0 0 0 0 % S
% Thr: 50 30 0 0 0 0 0 0 30 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 10 50 30 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 10 50 30 0 0 0 0 % W
% Tyr: 0 50 40 0 0 0 40 40 0 0 50 30 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _