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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOXB5
All Species:
30
Human Site:
S259
Identified Species:
55
UniProt:
P09067
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09067
NP_002138.1
269
29434
S259
D
N
K
L
K
S
M
S
L
A
T
A
G
S
A
Chimpanzee
Pan troglodytes
XP_001162719
274
29731
S264
D
N
K
L
K
S
M
S
M
A
A
A
G
G
A
Rhesus Macaque
Macaca mulatta
XP_001092568
274
29786
S264
D
N
K
L
K
S
M
S
M
A
A
A
G
G
A
Dog
Lupus familis
XP_548176
269
29426
S259
D
N
K
L
K
S
M
S
L
A
T
A
G
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P09079
269
29446
S259
D
N
K
L
K
S
M
S
L
A
T
A
G
S
A
Rat
Rattus norvegicus
P52949
233
25338
N224
Q
I
K
I
W
F
Q
N
R
R
M
K
W
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510583
590
66471
Q478
N
I
R
Y
R
S
I
Q
T
T
S
S
Q
N
S
Chicken
Gallus gallus
Q6B3N0
270
29723
S260
D
N
K
L
K
S
M
S
M
A
A
A
G
G
A
Frog
Xenopus laevis
P09019
230
25257
L221
N
K
L
K
S
M
S
L
A
T
G
S
S
A
F
Zebra Danio
Brachydanio rerio
P09014
275
30539
S265
D
N
K
L
K
S
M
S
L
A
T
A
G
S
A
Tiger Blowfish
Takifugu rubipres
Q1KKX0
280
30954
S270
D
N
K
L
K
S
M
S
L
V
T
G
G
S
A
Fruit Fly
Dros. melanogaster
P09077
417
44245
N389
E
H
K
M
A
S
M
N
I
V
P
Y
H
M
G
Honey Bee
Apis mellifera
P15859
86
10695
Y77
A
S
M
N
I
V
P
Y
H
M
S
P
Y
G
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.7
58.7
99.6
N.A.
98.8
48.7
N.A.
27.6
62.2
56.8
73.8
68.2
30.4
24.5
N.A.
N.A.
Protein Similarity:
100
70.8
70.8
99.6
N.A.
98.8
59.1
N.A.
35.5
72.9
67.2
83.2
77.5
42.2
28.2
N.A.
N.A.
P-Site Identity:
100
80
80
100
N.A.
100
6.6
N.A.
6.6
80
0
100
86.6
20
0
N.A.
N.A.
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
20
N.A.
60
86.6
20
100
86.6
53.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
8
54
24
54
0
8
62
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
8
62
31
8
% G
% His:
0
8
0
0
0
0
0
0
8
0
0
0
8
0
8
% H
% Ile:
0
16
0
8
8
0
8
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
77
8
62
0
0
0
0
0
0
8
0
8
8
% K
% Leu:
0
0
8
62
0
0
0
8
39
0
0
0
0
0
0
% L
% Met:
0
0
8
8
0
8
70
0
24
8
8
0
0
8
0
% M
% Asn:
16
62
0
8
0
0
0
16
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
8
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
8
0
8
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
0
8
0
0
8
77
8
62
0
0
16
16
8
39
8
% S
% Thr:
0
0
0
0
0
0
0
0
8
16
39
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _