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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO2
All Species:
40.91
Human Site:
Y257
Identified Species:
69.23
UniProt:
P09104
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09104
NP_001966.1
434
47269
Y257
E
F
Y
R
D
G
K
Y
D
L
D
F
K
S
P
Chimpanzee
Pan troglodytes
XP_511294
434
46968
Y257
E
F
Y
R
N
G
K
Y
D
L
D
F
K
S
P
Rhesus Macaque
Macaca mulatta
XP_001110839
434
47224
Y257
E
F
H
R
D
G
K
Y
D
L
D
F
K
S
P
Dog
Lupus familis
XP_534902
434
47168
Y257
E
F
H
R
D
G
K
Y
D
L
D
F
K
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P17183
434
47278
Y257
E
F
Y
R
D
G
K
Y
D
L
D
F
K
S
P
Rat
Rattus norvegicus
P07323
434
47122
Y257
E
F
Y
R
D
G
K
Y
D
L
D
F
K
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505468
461
50129
Y257
E
F
Y
R
D
G
K
Y
D
L
D
F
K
S
P
Chicken
Gallus gallus
O57391
434
47290
Y257
E
F
Y
R
D
G
K
Y
D
L
D
F
K
S
P
Frog
Xenopus laevis
P08734
434
47486
Y257
E
F
Y
R
D
G
K
Y
D
L
D
F
K
S
P
Zebra Danio
Brachydanio rerio
NP_001003848
434
46822
Y257
E
F
Y
R
E
G
K
Y
D
L
D
F
K
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15007
500
54292
D325
F
Y
K
D
G
Q
Y
D
L
D
F
K
N
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27527
434
46598
D258
F
F
K
D
G
K
Y
D
L
D
F
K
N
P
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P42895
446
48144
Q263
E
F
Y
S
D
K
D
Q
T
Y
D
L
N
F
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P25696
444
47701
D264
Y
S
E
D
K
T
Y
D
L
N
F
K
E
E
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.4
99.3
98.8
N.A.
98.6
97.9
N.A.
79.6
91.4
82.2
83.6
N.A.
63.2
N.A.
73.5
N.A.
Protein Similarity:
100
91.9
99.5
99.7
N.A.
99.5
99.5
N.A.
86.9
96.5
90.5
92.6
N.A.
73
N.A.
85.2
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
6.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
67.9
N.A.
68.9
N.A.
N.A.
Protein Similarity:
N.A.
79.6
N.A.
79.7
N.A.
N.A.
P-Site Identity:
N.A.
33.3
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
22
65
0
8
22
72
15
79
0
0
0
0
% D
% Glu:
79
0
8
0
8
0
0
0
0
0
0
0
8
15
0
% E
% Phe:
15
86
0
0
0
0
0
0
0
0
22
72
0
8
0
% F
% Gly:
0
0
0
0
15
72
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
15
0
8
15
72
0
0
0
0
22
72
0
15
% K
% Leu:
0
0
0
0
0
0
0
0
22
72
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
0
0
22
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
72
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
72
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
8
0
0
0
0
0
0
0
0
0
72
0
% S
% Thr:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
65
0
0
0
22
72
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _