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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACAA1 All Species: 42.73
Human Site: S154 Identified Species: 72.31
UniProt: P09110 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09110 NP_001123882.1 424 44292 S154 A C G V E S M S L A D R G N P
Chimpanzee Pan troglodytes XP_001171310 424 44347 S154 A C G V E S M S L A D R G N P
Rhesus Macaque Macaca mulatta XP_001088834 424 44308 S154 A C G V E S M S L A D R G N P
Dog Lupus familis XP_534222 426 44065 S156 A C G V E S M S L A D R G N P
Cat Felis silvestris
Mouse Mus musculus Q8VCH0 424 43977 T154 A C G V E S M T L S Q R G N H
Rat Rattus norvegicus P07871 424 43802 T154 A C G V E S M T L S E R G N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232577 426 43945 S162 A C G V E T M S L R S G N N P
Frog Xenopus laevis NP_001080604 419 43740 S149 A C G M E S M S L R S V G S P
Zebra Danio Brachydanio rerio NP_001002207 418 43985 S148 A C G V E S M S L R S P N N P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200436 367 38364 T116 P K V M L D Q T T K D C L I P
Poplar Tree Populus trichocarpa XP_002299284 460 48692 T167 G A G L E S M T I N Q M S W D
Maize Zea mays NP_001131193 461 47940 S168 G A G L E S M S I N S I A W E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LF48 443 46593 T161 G A G L E S M T T N P R G W K
Baker's Yeast Sacchar. cerevisiae P27796 417 44712 T156 A L G V E S M T N N Y K N V N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.5 91.7 N.A. 85.8 87 N.A. N.A. 78.6 73.5 72.4 N.A. N.A. N.A. N.A. 59.4
Protein Similarity: 100 99.7 99 94.5 N.A. 92.4 93.4 N.A. N.A. 88.7 86.3 83.2 N.A. N.A. N.A. N.A. 70.9
P-Site Identity: 100 100 100 100 N.A. 73.3 80 N.A. N.A. 66.6 66.6 73.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 100 N.A. N.A. 73.3 80 73.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 52.1 52.9 N.A. 54.8 51.8 N.A.
Protein Similarity: 68.7 67.6 N.A. 71.3 65.5 N.A.
P-Site Identity: 26.6 33.3 N.A. 40 40 N.A.
P-Site Similarity: 46.6 46.6 N.A. 53.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 72 22 0 0 0 0 0 0 0 29 0 0 8 0 0 % A
% Cys: 0 65 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 36 0 0 0 8 % D
% Glu: 0 0 0 0 93 0 0 0 0 0 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 22 0 93 0 0 0 0 0 0 0 0 8 58 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 15 0 0 8 0 8 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 8 0 8 0 0 8 % K
% Leu: 0 8 0 22 8 0 0 0 65 0 0 0 8 0 0 % L
% Met: 0 0 0 15 0 0 93 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 29 0 0 22 58 8 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 8 8 0 0 65 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 15 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 22 0 50 0 0 0 % R
% Ser: 0 0 0 0 0 86 0 58 0 15 29 0 8 8 0 % S
% Thr: 0 0 0 0 0 8 0 43 15 0 0 0 0 0 0 % T
% Val: 0 0 8 65 0 0 0 0 0 0 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 22 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _