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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACAA1 All Species: 27.58
Human Site: S251 Identified Species: 46.67
UniProt: P09110 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09110 NP_001123882.1 424 44292 S251 Q D E G I R P S T T M E G L A
Chimpanzee Pan troglodytes XP_001171310 424 44347 S251 Q D E G I R P S T T M E G L A
Rhesus Macaque Macaca mulatta XP_001088834 424 44308 S251 Q D E G I R P S T T M E G L A
Dog Lupus familis XP_534222 426 44065 N253 Q D E G I R P N T T M E G L A
Cat Felis silvestris
Mouse Mus musculus Q8VCH0 424 43977 S251 Q D E G V R P S T T M Q G L A
Rat Rattus norvegicus P07871 424 43802 S251 Q D E G V R P S T T M E G L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232577 426 43945 S259 Q D E G V R P S T T L E G L A
Frog Xenopus laevis NP_001080604 419 43740 S246 E D E G V R A S T T M E G L S
Zebra Danio Brachydanio rerio NP_001002207 418 43985 G245 K D D G I R P G T T L E G L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200436 367 38364 E210 L K P A F S P E G T T T A G N
Poplar Tree Populus trichocarpa XP_002299284 460 48692 P264 S V D D G I R P E T S V A G L
Maize Zea mays NP_001131193 461 47940 P265 S V D D G I R P G T T A S G L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LF48 443 46593 P258 S V D D G I R P N T T L S G L
Baker's Yeast Sacchar. cerevisiae P27796 417 44712 T250 E G P R P N V T A E S L S S I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.5 91.7 N.A. 85.8 87 N.A. N.A. 78.6 73.5 72.4 N.A. N.A. N.A. N.A. 59.4
Protein Similarity: 100 99.7 99 94.5 N.A. 92.4 93.4 N.A. N.A. 88.7 86.3 83.2 N.A. N.A. N.A. N.A. 70.9
P-Site Identity: 100 100 100 93.3 N.A. 86.6 93.3 N.A. N.A. 86.6 73.3 73.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 93.3 93.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 52.1 52.9 N.A. 54.8 51.8 N.A.
Protein Similarity: 68.7 67.6 N.A. 71.3 65.5 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: 13.3 13.3 N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 8 0 8 0 0 8 15 0 58 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 65 29 22 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 15 0 58 0 0 0 0 8 8 8 0 58 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 65 22 0 0 8 15 0 0 0 65 29 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 36 22 0 0 0 0 0 0 0 0 8 % I
% Lys: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 0 0 15 15 0 65 22 % L
% Met: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 8 0 0 0 0 0 8 % N
% Pro: 0 0 15 0 8 0 65 22 0 0 0 0 0 0 0 % P
% Gln: 50 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 0 8 0 65 22 0 0 0 0 0 0 0 0 % R
% Ser: 22 0 0 0 0 8 0 50 0 0 15 0 22 8 8 % S
% Thr: 0 0 0 0 0 0 0 8 65 93 22 8 0 0 0 % T
% Val: 0 22 0 0 29 0 8 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _