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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAA1
All Species:
28.48
Human Site:
T229
Identified Species:
48.21
UniProt:
P09110
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09110
NP_001123882.1
424
44292
T229
E
I
V
P
V
T
T
T
V
H
D
D
K
G
T
Chimpanzee
Pan troglodytes
XP_001171310
424
44347
T229
E
I
V
P
V
T
T
T
V
H
D
D
K
G
T
Rhesus Macaque
Macaca mulatta
XP_001088834
424
44308
T229
E
I
V
P
V
T
T
T
V
H
D
D
K
G
T
Dog
Lupus familis
XP_534222
426
44065
T231
E
I
V
P
V
T
T
T
V
H
D
D
K
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCH0
424
43977
T229
E
I
V
P
V
T
T
T
V
L
N
D
K
G
D
Rat
Rattus norvegicus
P07871
424
43802
T229
E
I
V
P
V
T
T
T
V
L
D
D
K
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232577
426
43945
T237
E
I
V
P
V
K
T
T
V
L
D
N
E
G
N
Frog
Xenopus laevis
NP_001080604
419
43740
T224
E
I
V
P
V
T
T
T
F
T
D
D
Q
G
N
Zebra Danio
Brachydanio rerio
NP_001002207
418
43985
K223
E
I
T
P
V
T
T
K
F
V
E
E
N
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200436
367
38364
D188
R
P
I
T
V
T
K
D
D
G
V
R
G
N
T
Poplar Tree
Populus trichocarpa
XP_002299284
460
48692
K242
E
I
I
P
V
A
T
K
I
V
D
P
K
T
G
Maize
Zea mays
NP_001131193
461
47940
K243
E
I
V
P
V
P
T
K
I
V
D
P
K
T
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LF48
443
46593
K236
E
I
T
P
V
K
T
K
I
V
D
P
K
T
G
Baker's Yeast
Sacchar. cerevisiae
P27796
417
44712
I228
E
G
L
F
E
D
E
I
L
P
I
K
L
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.5
91.7
N.A.
85.8
87
N.A.
N.A.
78.6
73.5
72.4
N.A.
N.A.
N.A.
N.A.
59.4
Protein Similarity:
100
99.7
99
94.5
N.A.
92.4
93.4
N.A.
N.A.
88.7
86.3
83.2
N.A.
N.A.
N.A.
N.A.
70.9
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
N.A.
66.6
73.3
53.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
80
80
66.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
52.1
52.9
N.A.
54.8
51.8
N.A.
Protein Similarity:
68.7
67.6
N.A.
71.3
65.5
N.A.
P-Site Identity:
46.6
53.3
N.A.
46.6
6.6
N.A.
P-Site Similarity:
60
60
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
8
8
0
72
50
0
0
22
% D
% Glu:
93
0
0
0
8
0
8
0
0
0
8
8
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
15
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
8
0
0
8
65
22
% G
% His:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% H
% Ile:
0
86
15
0
0
0
0
8
22
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
15
8
29
0
0
0
8
65
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
8
22
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
8
8
8
15
% N
% Pro:
0
8
0
86
0
8
0
0
0
8
0
22
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
15
8
0
65
86
58
0
8
0
0
0
22
36
% T
% Val:
0
0
65
0
93
0
0
0
50
29
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _